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Rebeca Martinez
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Kenia Ubieta Biotechnology Animal Division, Biochemistry Department, Physico-Chemistry Division, Aquatic Biotechnology Department, CIGB, PO Box 6162, Havana 10600, Cuba

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Fidel Herrera
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Alina Forellat Biotechnology Animal Division, Biochemistry Department, Physico-Chemistry Division, Aquatic Biotechnology Department, CIGB, PO Box 6162, Havana 10600, Cuba

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Reynold Morales
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Ania de la Nuez Biotechnology Animal Division, Biochemistry Department, Physico-Chemistry Division, Aquatic Biotechnology Department, CIGB, PO Box 6162, Havana 10600, Cuba

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Rolando Rodriguez Biotechnology Animal Division, Biochemistry Department, Physico-Chemistry Division, Aquatic Biotechnology Department, CIGB, PO Box 6162, Havana 10600, Cuba

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Osvaldo Reyes Biotechnology Animal Division, Biochemistry Department, Physico-Chemistry Division, Aquatic Biotechnology Department, CIGB, PO Box 6162, Havana 10600, Cuba

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Ayme Oliva
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Mario P Estrada
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modulation of antioxidant activity due to variations in energy metabolism ( Wilhelm Filho et al . 1993 , Martínez-Alvarez et al . 2005 ). Administration or overexpression of GH produced a significant increase in metabolic rate and oxygen consumption in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0373
Volume/Issue:
Volume 214: Issue 3
Free access
Ralf Baumeister Bio 3, Bioinformatics and Molecular Genetics, University of Freiburg, Germany
ZBSA – Freiburg Center for Systems Biology, University of Freiburg, Germany
Renal Division, University Hospital Freiburg, Germany

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Elke Schaffitzel Bio 3, Bioinformatics and Molecular Genetics, University of Freiburg, Germany
ZBSA – Freiburg Center for Systems Biology, University of Freiburg, Germany
Renal Division, University Hospital Freiburg, Germany

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Maren Hertweck Bio 3, Bioinformatics and Molecular Genetics, University of Freiburg, Germany
ZBSA – Freiburg Center for Systems Biology, University of Freiburg, Germany
Renal Division, University Hospital Freiburg, Germany

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as a superb model to understand the mechanisms through which DR can affect longevity. It has been suggested that DR not only reduces both the metabolic rate and intracellular homeostasis of both sugars and amino acids, but also directly influences

Article Type:
Review Article
DOI:
https://doi.org/10.1677/joe.1.06856
Volume/Issue:
Volume 190: Issue 2
Free access
Matthew J VandeKopple Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA

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Jinghai Wu Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA

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Lisa A Baer Dorothy M. Davis Heart and Lung Research Institute, Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA

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Naresh C Bal Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA

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Santosh K Maurya Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA

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Anuradha Kalyanasundaram Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA

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Muthu Periasamy Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA

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Kristin I Stanford Dorothy M. Davis Heart and Lung Research Institute, Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA

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Amato J Giaccia Department of Radiation Oncology, Stanford University, Stanford, CA, USA

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Nicholas C Denko Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA

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Ioanna Papandreou Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA

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minimize heat loss (for example, presence of fur, nesting, changes in body posture) and actively increase heat production. In the initial response to a cold environment, mammals significantly increase their metabolic rate and initiate a shivering response

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0289
Volume/Issue:
Volume 235: Issue 1
Free access
Gustavo W Fernandes
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Cintia B Ueta Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Tatiane L Fonseca Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Cecilia H A Gouveia Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Carmen L Lancellotti Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Patrícia C Brum Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Marcelo A Christoffolete Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Antonio C Bianco Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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Miriam O Ribeiro Presbyterian University Mackenzie – Biological Science, Institute of Science Biomedical – Morpho-Functional Sciences, Department of Cell and Developmental Biology, Department of Anatomy, Santa Casa – AFIP and Pathology, School of Physical Education and Sport, Federal University of ABC – Human and Natural Sciences Center, Division of Endocrinology, Ciências Biológicas e da Saúde, CCBS, São Paulo, SP, Brazil

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vivo given that mice with ARβ 3 KO exhibit only a modest increase in body fat, have normal basal metabolic rate, and respond normally to cold exposure ( Susulic et al . 1995 ), which could be due to upregulation of ARβ 1 ( Atgie et al . 1997

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0526
Volume/Issue:
Volume 221: Issue 3
Free access
Keld Fosgerau Novo Nordisk Diabetes Research Unit, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

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Kirsten Raun Novo Nordisk Diabetes Research Unit, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

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Cecilia Nilsson Novo Nordisk Diabetes Research Unit, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

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Kirsten Dahl Novo Nordisk Diabetes Research Unit, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

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Birgitte S Wulff Novo Nordisk Diabetes Research Unit, Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

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MC4-R agonists leads to a suppression of appetite and increases the metabolic rate resulting in a significant weight loss ( Li et al . 2004 ). Furthermore mice, rats, and humans deficient in the MC4-R are obese ( Huszar et al . 1997 , Vaisse et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0284
Volume/Issue:
Volume 220: Issue 2
Open access
Xinyu Qi Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing, China

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Chuyu Yun Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, School of Basic Medical Sciences, Peking University, Beijing, China

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Baoying Liao Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing, China
Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China

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Jie Qiao Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing, China
Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China
National Clinical Research Center for Obstetrics and Gynecology, Beijing, China
Research Units of Comprehensive Diagnosis and Treatment of Oocyte Maturation Arrest, Beijing, China

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Yanli Pang Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing, China
Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China

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increase the metabolic rate and improve insulin resistance ( Bartelt & Heeren 2014 , Brestoff & Artis 2015 ). White adipose tissue browning increases the metabolic rate and improves insulin resistance ( Fang et al. 2015 ). A recent study revealed that

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0589
Volume/Issue:
Volume 245: Issue 2
Restricted access
Raquel Barbuio Department of Internal Medicine and Gastrocentro, State University of Campinas, Campinas, SP 13083–970, Brazil

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Marciane Milanski Department of Internal Medicine and Gastrocentro, State University of Campinas, Campinas, SP 13083–970, Brazil

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Manoel B Bertolo Department of Internal Medicine and Gastrocentro, State University of Campinas, Campinas, SP 13083–970, Brazil

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Mário J Saad Department of Internal Medicine and Gastrocentro, State University of Campinas, Campinas, SP 13083–970, Brazil

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Lício A Velloso Department of Internal Medicine and Gastrocentro, State University of Campinas, Campinas, SP 13083–970, Brazil

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selected for treatment with saline (100 μ l/dose, i.p., twice a day) or with infliximab (100 μ g in 100 μ l saline/dose, i.p., twice a day). The infliximab dose was adjusted for rat metabolic rates, as compared with human metabolic rates (in clinical

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0234
Volume/Issue:
Volume 194: Issue 3
Free access
Munetaka Shimizu Northwest Fisheries Science Center, NOAA Fisheries, 2725 Montlake Boulevard East, Seattle, Washington 98112, USA
School of Aquatic and Fishery Sciences, University of Washington, Seattle, Washington 98195, USA
Graduate School of Fisheries Sciences, Hokkaido University, 3-1–1 Minato, Hakodate, Hokkaido 041-8611, Japan

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Brian R Beckman Northwest Fisheries Science Center, NOAA Fisheries, 2725 Montlake Boulevard East, Seattle, Washington 98112, USA
School of Aquatic and Fishery Sciences, University of Washington, Seattle, Washington 98195, USA
Graduate School of Fisheries Sciences, Hokkaido University, 3-1–1 Minato, Hakodate, Hokkaido 041-8611, Japan

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Akihiko Hara Northwest Fisheries Science Center, NOAA Fisheries, 2725 Montlake Boulevard East, Seattle, Washington 98112, USA
School of Aquatic and Fishery Sciences, University of Washington, Seattle, Washington 98195, USA
Graduate School of Fisheries Sciences, Hokkaido University, 3-1–1 Minato, Hakodate, Hokkaido 041-8611, Japan

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Walton W Dickhoff Northwest Fisheries Science Center, NOAA Fisheries, 2725 Montlake Boulevard East, Seattle, Washington 98112, USA
School of Aquatic and Fishery Sciences, University of Washington, Seattle, Washington 98195, USA
Graduate School of Fisheries Sciences, Hokkaido University, 3-1–1 Minato, Hakodate, Hokkaido 041-8611, Japan

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, suggesting that IGFBP-1 may be more sensitive than IGF-I to ration change. Overall, the results indicate that IGFBP-1 is quite responsive to moderate ration change in salmon. Environmental temperature is a crucial factor affecting metabolic rate of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06475
Volume/Issue:
Volume 188: Issue 1
Free access
Michael Rosenbaum Division of Molecular Genetics, Departments of Pediatrics and Medicine, College of Physicians and Surgeons, Columbia University, Russ Berrie Medical Science Pavilion, 6th Floor, 1150 St Nicholas Avenue, New York, New York 10032, USA

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Rudolph L Leibel Division of Molecular Genetics, Departments of Pediatrics and Medicine, College of Physicians and Surgeons, Columbia University, Russ Berrie Medical Science Pavilion, 6th Floor, 1150 St Nicholas Avenue, New York, New York 10032, USA

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, Zelissen et al . 2005 ) (resulting in leptin concentrations similar to baseline concentrations) induced significant changes in body weight changes, resting metabolic rate, or hunger compared with placebo in subjects prescribed a 500 kcal/day caloric

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-14-0358
Volume/Issue:
Volume 223: Issue 1
Free access
David A Bechtold Faculty of Life Sciences, University of Manchester, 1.124 Stopford Building, Oxford Road, Manchester M13 9PT, UK

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Simon M Luckman Faculty of Life Sciences, University of Manchester, 1.124 Stopford Building, Oxford Road, Manchester M13 9PT, UK

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expenditure. Furthermore, GPR10-knockout mice exhibit a much lower basal metabolic rate, when compared with wild-type mice (our unpublished observations), which likely contributes to the development of obesity in these animals ( Gu et al. 2004

Article Type:
Review Article
DOI:
https://doi.org/10.1677/JOE-06-0069
Volume/Issue:
Volume 192: Issue 1
Free access