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Tracy Xiao Cui, Roland Kwok, and Jessica Schwartz

) and an adjacent CCAAT/enhancer-binding protein (C/EBP) site, and an activator protein-1 (AP-1) site; these elements can be bound by cognate transcription factors to regulate c- fos transcription in response to GH ( Meyer et al . 1993 , 1994

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O Schakman, H Gilson, and J P Thissen

transcription factor mandatory for differentia tion of satellite cells into muscle fibers ( te Pas et al . 2000 ). Catabolic action of glucocorticoids The stimulatory effect of glucocorticoids on muscle proteolysis results from the activation of the major

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Nadia Schoenmakers, Kyriaki S Alatzoglou, V Krishna Chatterjee, and Mehul T Dattani

) ( Garcia et al . 2014 ). Alternatively, as normal pituitary development depends on the sequential temporal and spatial expression of a cascade of signaling molecules and transcription factors, mutations in early ( HESX1, LHX3, LHX4, SOX3, OTX2 ) or late

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Y Kamei, Y Aoyama, T Fujimoto, N Kenmotsu, C Kishi, M Koushi, S Sugano, K Morohashi, R Kamiyama, and R Asakai

, whereas GC lines lacking steroidogenesis completely lose the expression of this transcription factor ( Keren-Tal et al. 1997 ). These data account only for the role of Ad4BP in steroidogenesis and organogenesis, but it still remains unclear whether Ad4BP

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Bohan Wang, I Stuart Wood, and Paul Trayhurn

transcriptional regulation by the hypoxia-inducible transcription factor, HIF-1 ( Grosfeld et al . 2001 , Ambrosini et al . 2002 ). The induction of leptin expression by hypoxia has also been reported in other cell types, including human trophoblast cell lines

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Myat Theingi Swe, Laongdao Thongnak, Krit Jaikumkao, Anchalee Pongchaidecha, Varanuj Chatsudthipong, and Anusorn Lungkaphin

renal cortical tissue in HF rats was attenuated by dapagliflozin and metformin administration ( P  < 0.05) ( Fig. 1I and J ). The effect of dapagliflozin on renal gluconeogenic enzyme expression might be mediated through transcription factors p

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Gonzalo Alba, Consuelo Santa-María, María Edith Reyes-Quiroz, Rajaa El Bekay, Isabel Geniz, José Martín-Nieto, Elizabeth Pintado, and Francisco Sobrino

. Although high concentrations of ROS are catatonic, they are now known to function as signal transducing molecules at lower concentrations, modulating indirectly the activity of many enzymes and transcription factors. Classical regulation of the activity of

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Almas R Juma, Pauliina E Damdimopoulou, Sylvia V H Grommen, Wim J M Van de Ven, and Bert De Groef

Introduction The transcription factor pleomorphic adenoma gene 1 (PLAG1) was first discovered via positional cloning when researchers were studying pleomorphic adenomas of the salivary glands ( Kas et al . 1997 ). Its role in various types of

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Hyunju Chung and Seungjoon Park

transcription factor E2F1 is involved in the regulation of cell cycle regulation ( Yoshikawa 2000 ). Additionally, the activity of cyclin–CDK complex can be regulated by the inhibitory interaction with CDK inhibitors (CKIs), such as p21 CIP1 , p27 KIP1 and p57

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Akiko Mizokami, Satoru Mukai, Jing Gao, Tomoyo Kawakubo-Yasukochi, Takahito Otani, Hiroshi Takeuchi, Eijiro Jimi, and Masato Hirata

.01 (Student’s t test). We previously showed that GluOC activates the transcription factor CREB (cAMP response element–binding protein) and increases the expression of the transcription factor FoxO1 (forkhead box protein O1) in 3T3-L1 adipocytes