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the report. Quantitative PCR Total RNA was isolated from cell cultures or flash frozen femurs of 16-week-old mice using TRIzol (Life Technologies) method for tissues. Bone marrow contents were not flushed out from femurs prior to RNA isolation
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may have a generalised effect on adipose tissue physiology ( Korostishevsky et al. 2010 ). These data support the concept that ANK is a critical player in the complex network connecting bone, adipose tissue and P i metabolism. PHOSPHO1 is
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Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA
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Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA
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( Prisby et al . 2008 ) and is one basis for the decrease in mechanical strength of long bones in the hindlimb. It has been proposed that one contributing factor to this decrease in BMD and mechanical strength could be a reduction in bone and marrow blood
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.ejphar.2009.10.045 . Wang M Crisostomo PR Herring C Meldrum KK Meldrum DR 2006 Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-1 in response to TNF by a p38 MAPK-dependent mechanism . American Journal of
Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA
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Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA
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2014 Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction . Cell Metabolism 20 368 – 375 . ( doi:10.1016/j.cmet.2014.06.003 ) Chen KY Brychta RJ
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Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium
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Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium
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has doubled since 1980 ( Pi-Sunyer 2002 , Karlsson & Beck 2010 ). In this context, a better understanding of adipose tissue biology could contribute to the control of energy metabolism and obesity, at least in the most extreme situations. White
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Adipose tissue browning and whitening A hallmark feature of adipose tissue browning is the induction of thermogenically active adipocytes in white fat depots. These adipocytes are often referred to as beige or brite (brown in white) cells and
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after surgery. Femora and tibiae were removed aseptically and dissected free of adherent soft tissue. The marrow cavity was washed with α-MEM from one end of the bone using a sterile 21-gauge needle after dissecting the bone ends, and a single
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Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden
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), which increases expression of peroxisome proliferator-activated receptor gamma 2 (PPARγ2) and suppresses the expression of Runx2 ( Canalis et al. 2004 , 2007 ). GCs may, therefore, increase bone marrow adipose tissue at the expense of mature
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Institute of Biomedicine, University of Barcelona, Barcelona, Spain
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Institute of Biomedicine, University of Barcelona, Barcelona, Spain
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Department of Endocrinology and Nutrition, Hospital Clinic of Barcelona, Barcelona, Spain
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Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain
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-1214 ) Hamrick MW McGee-Lawrence ME Frechette DM 2016 Fatty infiltration of skeletal muscle: mechanisms and comparisons with bone marrow adiposity . Frontiers in Endocrinology 7 69 . ( https://doi.org/10.3389/fendo.2016.00069 ) 27379021 Henneicke