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David E Maridas Maine Medical Center Research Institute, Scarborough, Maine, USA

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Victoria E DeMambro Maine Medical Center Research Institute, Scarborough, Maine, USA

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Phuong T Le Maine Medical Center Research Institute, Scarborough, Maine, USA

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Kenichi Nagano Harvard School of Dental Medicine, Boston, Massachusetts, USA

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Roland Baron Harvard School of Dental Medicine, Boston, Massachusetts, USA

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Subburaman Mohan VA Loma Linda Healthcare System, Loma Linda, California, USA

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Clifford J Rosen Maine Medical Center Research Institute, Scarborough, Maine, USA

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the report. Quantitative PCR Total RNA was isolated from cell cultures or flash frozen femurs of 16-week-old mice using TRIzol (Life Technologies) method for tissues. Bone marrow contents were not flushed out from femurs prior to RNA isolation

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0673
Volume/Issue:
Volume 233: Issue 1
Open access
Fiona Roberts Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Greg Markby Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Scott Dillon Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Colin Farquharson Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Vicky E MacRae Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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may have a generalised effect on adipose tissue physiology ( Korostishevsky et al. 2010 ). These data support the concept that ANK is a critical player in the complex network connecting bone, adipose tissue and P i metabolism. PHOSPHO1 is

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0460
Volume/Issue:
Volume 245: Issue 2
Free access
John N Stabley Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA

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Rhonda D Prisby Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA

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Bradley J Behnke Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA
Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA

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Michael D Delp Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA
Department of Applied Physiology and Kinesiology, Department of Kinesiology and Applied Physiology, Department of Kinesiology, Department of Nutrition, University of Florida, Gainesville, Florida 32611, USA

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( Prisby et al . 2008 ) and is one basis for the decrease in mechanical strength of long bones in the hindlimb. It has been proposed that one contributing factor to this decrease in BMD and mechanical strength could be a reduction in bone and marrow blood

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0514
Volume/Issue:
Volume 225: Issue 1
Free access
Toshiaki Ishizuka Department of Pharmacology, National Defense Medical College, 3-2, Namiki, Tokorozawa, Saitama 359-8513, Japan

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Takashi Hinata Department of Pharmacology, National Defense Medical College, 3-2, Namiki, Tokorozawa, Saitama 359-8513, Japan

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Yasuhiro Watanabe Department of Pharmacology, National Defense Medical College, 3-2, Namiki, Tokorozawa, Saitama 359-8513, Japan

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.ejphar.2009.10.045 . Wang M Crisostomo PR Herring C Meldrum KK Meldrum DR 2006 Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-1 in response to TNF by a p38 MAPK-dependent mechanism . American Journal of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0305
Volume/Issue:
Volume 208: Issue 2
Free access
Margo P Emont Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA
Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA

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Hui Yu Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA

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Jun Wu Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA
Life Sciences Institute, Department of Molecular and Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, LSI, RM5115A, Ann Arbor, Michigan 48109, USA

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2014 Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction . Cell Metabolism 20 368 – 375 . ( doi:10.1016/j.cmet.2014.06.003 ) Chen KY Brychta RJ

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-15-0026
Volume/Issue:
Volume 225: Issue 2
Free access
Laurie Rouger Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium

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G Raphaël Denis Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium

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Souphalone Luangsay Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium
Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium

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Marc Parmentier Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium
Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, WELBIO, Université Paris Diderot, Euroscreen SA, Université Libre de Bruxelles, Campus Erasme, Route de Lennik 808, B-1070 Brussels, Belgium

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has doubled since 1980 ( Pi-Sunyer 2002 , Karlsson & Beck 2010 ). In this context, a better understanding of adipose tissue biology could contribute to the control of energy metabolism and obesity, at least in the most extreme situations. White

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0106
Volume/Issue:
Volume 219: Issue 3
Free access
Ke Ke Department of Biological Sciences, University of Ulsan, Ulsan, Korea

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Ok-Joo Sul Department of Biological Sciences, University of Ulsan, Ulsan, Korea

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Soo-Wol Chung Department of Biological Sciences, University of Ulsan, Ulsan, Korea

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Jae-Hee Suh Department of Pathology, Ulsan University Hospital, Ulsan, Korea

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Hye-Seon Choi Department of Biological Sciences, University of Ulsan, Ulsan, Korea

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after surgery. Femora and tibiae were removed aseptically and dissected free of adherent soft tissue. The marrow cavity was washed with α-MEM from one end of the bone using a sterile 21-gauge needle after dissecting the bone ends, and a single

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0591
Volume/Issue:
Volume 235: Issue 2
Free access
Carsten T Herz Clinical Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria

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Florian W Kiefer Clinical Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria

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Adipose tissue browning and whitening A hallmark feature of adipose tissue browning is the induction of thermogenically active adipocytes in white fat depots. These adipocytes are often referred to as beige or brite (brown in white) cells and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0598
Volume/Issue:
Volume 241: Issue 3
Free access
Claire L Wood Division of Developmental Biology, Roslin Institute, University of Edinburgh, Edinburgh, UK

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Ondrej Soucek Department of Paediatrics, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic
Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden

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Sze C Wong Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK

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Farasat Zaman Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden

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Colin Farquharson Division of Developmental Biology, Roslin Institute, University of Edinburgh, Edinburgh, UK

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Lars Savendahl Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden

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S Faisal Ahmed Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK

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), which increases expression of peroxisome proliferator-activated receptor gamma 2 (PPARγ2) and suppresses the expression of Runx2 ( Canalis et al. 2004 , 2007 ). GCs may, therefore, increase bone marrow adipose tissue at the expense of mature

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-17-0361
Volume/Issue:
Volume 236: Issue 1
Free access
Guillermo García-Eguren Group of Endocrine Disorders, IDIBAPS, Barcelona, Spain

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Oriol Giró Group of Endocrine Disorders, IDIBAPS, Barcelona, Spain

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María del Mar Romero Department of Biochemistry and Molecular Biomedicine, Section of Nutrition, Faculty of Biology, University of Barcelona, Barcelona, Spain
Institute of Biomedicine, University of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Obesidad y Nutrición (CIBEROBN), Carlos III Health Institute, Madrid, Spain

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Mar Grasa Department of Biochemistry and Molecular Biomedicine, Section of Nutrition, Faculty of Biology, University of Barcelona, Barcelona, Spain
Institute of Biomedicine, University of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Obesidad y Nutrición (CIBEROBN), Carlos III Health Institute, Madrid, Spain

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Felicia A Hanzu Group of Endocrine Disorders, IDIBAPS, Barcelona, Spain
Department of Endocrinology and Nutrition, Hospital Clinic of Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain
Department of Medicine, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain

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-1214 ) Hamrick MW McGee-Lawrence ME Frechette DM 2016 Fatty infiltration of skeletal muscle: mechanisms and comparisons with bone marrow adiposity . Frontiers in Endocrinology 7 69 . ( https://doi.org/10.3389/fendo.2016.00069 ) 27379021 Henneicke

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0168
Volume/Issue:
Volume 242: Issue 2
Free access