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Sophie Fouchécourt INSERM U 418; INRA UMR 1245; Université Claude-Bernard Lyon 1, 29 rue Sœur Bouvier, 69322 Lyon Cedex 05, France
Faculté de Médécine, Centre Commun de Cytométrie en Flux, Université Jean Monnet, 42023 St Etienne, France

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Murielle Godet INSERM U 418; INRA UMR 1245; Université Claude-Bernard Lyon 1, 29 rue Sœur Bouvier, 69322 Lyon Cedex 05, France
Faculté de Médécine, Centre Commun de Cytométrie en Flux, Université Jean Monnet, 42023 St Etienne, France

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Odile Sabido INSERM U 418; INRA UMR 1245; Université Claude-Bernard Lyon 1, 29 rue Sœur Bouvier, 69322 Lyon Cedex 05, France
Faculté de Médécine, Centre Commun de Cytométrie en Flux, Université Jean Monnet, 42023 St Etienne, France

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Philippe Durand INSERM U 418; INRA UMR 1245; Université Claude-Bernard Lyon 1, 29 rue Sœur Bouvier, 69322 Lyon Cedex 05, France
Faculté de Médécine, Centre Commun de Cytométrie en Flux, Université Jean Monnet, 42023 St Etienne, France

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potential importance of the GDNF/RET pathway in male reproductive physiopathology, we determined the localization of GDNF and its two receptors, GFR1α and RET, during postnatal development of the rat testis. We determined mRNA and protein levels in isolated

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Natalia Pavón Departamento de Farmacología, Instituto Nacional de Cardiología Ignacio Chávez, México, Mexico

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Alfredo Cabrera-Orefice Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México D.F., Mexico

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Juan Carlos Gallardo-Pérez Departamento de Bioquímica, Instituto Nacional de Cardiología Ignacio Chávez, México, Mexico

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Cristina Uribe-Alvarez Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México D.F., Mexico

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Nadia A Rivero-Segura Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química UNAM, México D.F., Mexico

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Edgar Ricardo Vazquez-Martínez Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química UNAM, México D.F., Mexico

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Marco Cerbón Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química UNAM, México D.F., Mexico

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Eduardo Martínez-Abundis División Académica Multidisciplinaria de Comalcalco, Universidad Juárez Autónoma de Tabasco, México, Mexico

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Juan Carlos Torres-Narvaez Departamento de Farmacología, Instituto Nacional de Cardiología Ignacio Chávez, México, Mexico

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Raúl Martínez-Memije Departamento de Instrumentación Electromecánica, Instituto Nacional de Cardiología Ignacio Chávez, Tlalpan DF, México, Mexico

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Francisco-Javier Roldán-Gómez Departamento de Consulta externa, Instituto Nacional de Cardiología Ignacio Chávez, México, Mexico

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Salvador Uribe-Carvajal Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México D.F., Mexico

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disappears upon estradiol administration ( Duckles et al . 2006 ). Thus, we explored functional alterations in rat heart mitochondria at one, two and three months after oophorectomy. Oxygen consumption measurements were performed to analyze the progressive

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J M Mellado-Gil Endocrinology Service and Research Unit, Puerta del Mar Hospital, Cadiz, Spain

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M Aguilar-Diosdado Endocrinology Service and Research Unit, Puerta del Mar Hospital, Cadiz, Spain

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-1β in rat pancreatic islet cells. In addition, we explored the expression level of potentially related apoptotic and anti-apoptotic molecules in rat islet cells treated with these various cell death inducers and different glucose concentrations. Our

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Giuseppe Calamita Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Maria Moreno Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Domenico Ferri Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Elena Silvestri Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Patrizia Roberti Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Luigi Schiavo Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Patrizia Gena Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Maria Svelto Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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Fernando Goglia Department of General and Environmental Physiology, Università degli Studi di Bari, Via Amendola 165/A, 70126 Bari, Italy
Department of Biological and Environmental Sciences, University of Sannio, Via Port’Arsa 11, 82100 Benevento, Italy
Department of Zoology, University of Bari, Bari, Italy

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a ), mitochondria possess facilitated pathways for water diffusion other than the AQP8 water channels ( Calamita et al. 2006 ). In rat, liver AQP8 has also been suggested to play a role in amino acid metabolism and detoxification of ammonia by

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R L Bogorad Laboratory of Endocrinology, Faculty of Biology, Lomonosov Moscow State University, Vorob’ev Hills, 119992, Moscow, Russian Federation
Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation

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T Y Ostroukhova Laboratory of Endocrinology, Faculty of Biology, Lomonosov Moscow State University, Vorob’ev Hills, 119992, Moscow, Russian Federation
Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation

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A N Orlova Laboratory of Endocrinology, Faculty of Biology, Lomonosov Moscow State University, Vorob’ev Hills, 119992, Moscow, Russian Federation
Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation

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P M Rubtsov Laboratory of Endocrinology, Faculty of Biology, Lomonosov Moscow State University, Vorob’ev Hills, 119992, Moscow, Russian Federation
Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation

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O V Smirnova Laboratory of Endocrinology, Faculty of Biology, Lomonosov Moscow State University, Vorob’ev Hills, 119992, Moscow, Russian Federation
Laboratory of Hormones and Receptors, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova Str., 119991, Moscow, Russian Federation

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Introduction Several prolactin receptor (PrlR) isoforms have been identified in mammals. In rat, they have been shown to be produced via alternative splicing of PrlR pre-mRNA: the formation of long and short isoforms result from

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Andreas Nygaard Madsen
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Gitte Hansen
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Sarah Juel Paulsen
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Kirsten Lykkegaard
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Mads Tang-Christensen
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Harald S Hansen Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark

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Barry E Levin Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark
Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark

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Philip Just Larsen
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Lotte Bjerre Knudsen Rheoscience A/S, Faculty of Pharmaceutical Sciences, Neurology Service, Department of Neurology and Neurosciencies, NovoNordisk A/S, Rødovre 2610, Copenhagen, Denmark

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Keld Fosgerau
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Niels Vrang
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) out-bred rat models ( Levin et al . 1997 ). While some short-term studies have been performed to characterize the development of obesity and to address the presence of some of the associated metabolic disturbances ( Levin et al . 1997 , Levin

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Mélissa Otis Service of Endocrinology,
Department of Physiology and Biophysics, Faculty of Medicine and Health sciences, University of Sherbrooke, Sherbrooke, 3001, 12th Avenue North, Quebec, Canada J1H 5N4

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Shirley Campbell Service of Endocrinology,
Department of Physiology and Biophysics, Faculty of Medicine and Health sciences, University of Sherbrooke, Sherbrooke, 3001, 12th Avenue North, Quebec, Canada J1H 5N4

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Marcel D Payet Service of Endocrinology,
Department of Physiology and Biophysics, Faculty of Medicine and Health sciences, University of Sherbrooke, Sherbrooke, 3001, 12th Avenue North, Quebec, Canada J1H 5N4

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Nicole Gallo-Payet Service of Endocrinology,
Department of Physiology and Biophysics, Faculty of Medicine and Health sciences, University of Sherbrooke, Sherbrooke, 3001, 12th Avenue North, Quebec, Canada J1H 5N4

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Introduction The adult rat adrenal cortex is composed of three concentric layers, the zona glomerulosa, the zona fasciculata and the zona reticularis, all of which present different morphological and functional properties. The zona

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Simone Magagnin Wajner Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Márcia dos Santos Wagner Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Rossana C N Melo Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Gleydes G Parreira Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Hélio Chiarini-Garcia Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Antonio C Bianco Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Csaba Fekete Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Edith Sanchez Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Ronald M Lechan Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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Ana Luiza Maia Endocrine Division, Thyroid Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Laboratory of Cellular Biology, Department of Biology, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Laboratory of Structural Biology and Reproduction, Department of Morphology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest H-1083, Hungary
Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center, Boston, Massachusetts, USA

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testis was considered for years to be a thyroid hormone unresponsive organ, a concept based on data showing minimal levels of testicular thyroid hormone receptors (TRs) and lack of thyroid hormone effects on oxygen consumption in adult rat testes

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Andrei S Chagin Pediatric Endocrinology Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17176, Sweden

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Elham Karimian Pediatric Endocrinology Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17176, Sweden

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Katja Sundström Pediatric Endocrinology Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17176, Sweden

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Emma Eriksson Pediatric Endocrinology Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17176, Sweden

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Lars Sävendahl Pediatric Endocrinology Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Stockholm SE-17176, Sweden

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-up growth is still unclear. In the present work, we characterized an in vitro model that mimics the clinically observed catch-up growth after cessation of glucocorticoid exposure. For this purpose, we optimized a well-known model of fetal rat metatarsal

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Nikki P Y Lee Population Council, Center for Biomedical Research, 1230 York Avenue, New York, New York 10021, USA

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Dolores D Mruk Population Council, Center for Biomedical Research, 1230 York Avenue, New York, New York 10021, USA

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Weiliang Xia Population Council, Center for Biomedical Research, 1230 York Avenue, New York, New York 10021, USA

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C Yan Cheng Population Council, Center for Biomedical Research, 1230 York Avenue, New York, New York 10021, USA

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, Perry & Ridgway 2005 ), and it is vital to lipid metabolism in eukaryotic cells. SMS2 and its enzymatic activity have been extensively investigated in other systems, such as in chick liver ( Lyman et al. 1976 ), rat colon ( Dudeja et al. 1986 ), and

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