Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 61 - 70 of 221 items for :

  • sexual dimorphism x
  • Refine by access: All content x
Clear All
M Fraenkel Cedars-Sinai Research Institute, David Geffen School of Medicine at UCLA, 8700 Beverly Blvd, Los Angeles, California 90048, USA

Search for other papers by M Fraenkel in
Google Scholar
PubMed Close
,
J Caloyeras Cedars-Sinai Research Institute, David Geffen School of Medicine at UCLA, 8700 Beverly Blvd, Los Angeles, California 90048, USA

Search for other papers by J Caloyeras in
Google Scholar
PubMed Close
,
S-G Ren Cedars-Sinai Research Institute, David Geffen School of Medicine at UCLA, 8700 Beverly Blvd, Los Angeles, California 90048, USA

Search for other papers by S-G Ren in
Google Scholar
PubMed Close
, and
S Melmed Cedars-Sinai Research Institute, David Geffen School of Medicine at UCLA, 8700 Beverly Blvd, Los Angeles, California 90048, USA

Search for other papers by S Melmed in
Google Scholar
PubMed Close

+/+ control animals is likely secondary to the pttg -null lipodystrophy, which is caused primarily by the low insulin levels. Several studies in humans and rodents have shown sexual dimorphism in plasma levels of adiponectin, with males having lower levels

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06656
Volume/Issue:
Volume 189: Issue 3
Free access
Obaro Evuarherhe Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol BS1 3NY, UK

Search for other papers by Obaro Evuarherhe in
Google Scholar
PubMed Close
,
James Leggett Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol BS1 3NY, UK

Search for other papers by James Leggett in
Google Scholar
PubMed Close
,
Eleanor Waite Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol BS1 3NY, UK

Search for other papers by Eleanor Waite in
Google Scholar
PubMed Close
,
Yvonne Kershaw Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol BS1 3NY, UK

Search for other papers by Yvonne Kershaw in
Google Scholar
PubMed Close
, and
Stafford Lightman Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol BS1 3NY, UK

Search for other papers by Stafford Lightman in
Google Scholar
PubMed Close

number: RJ4534). References Atkinson HC Waddell BJ 1997 Circadian variation in basal plasma corticosterone and adrenocorticotropin in the rat: sexual dimorphism and changes across the estrous cycle . Endocrinology 138 3842 – 3848 . Azooz OG

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0175
Volume/Issue:
Volume 202: Issue 2
Free access
Sophie A Clarke Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

Search for other papers by Sophie A Clarke in
Google Scholar
PubMed Close
and
Waljit S Dhillo Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

Search for other papers by Waljit S Dhillo in
Google Scholar
PubMed Close

. Although the effects of kisspeptin in ageing populations remain largely unexplored, the kisspeptin neuron population in the infundibular nucleus clearly increases with time. Interestingly, however, in the same manner that sexual dimorphism exists with

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-15-0538
Volume/Issue:
Volume 229: Issue 3
Free access
Sara Della Torre Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

Search for other papers by Sara Della Torre in
Google Scholar
PubMed Close
,
Gianpaolo Rando Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

Search for other papers by Gianpaolo Rando in
Google Scholar
PubMed Close
,
Clara Meda Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

Search for other papers by Clara Meda in
Google Scholar
PubMed Close
,
Paolo Ciana Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy

Search for other papers by Paolo Ciana in
Google Scholar
PubMed Close
,
Luisa Ottobrini Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

Search for other papers by Luisa Ottobrini in
Google Scholar
PubMed Close
, and
Adriana Maggi Center of Excellence on Neurodegenerative Diseases, University of Milan, Milan, Italy
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy

Search for other papers by Adriana Maggi in
Google Scholar
PubMed Close

-temporal expression of ERα and ERβ was reported to contribute to organize sex differences that are not associated with reproduction, such as the stress response and cognition ( Mogi et al. 2015 ). It is conceivable that the sexual dimorphism observed in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0003
Volume/Issue:
Volume 238: Issue 3
Open access
Rajat Kumar Das Laboratories of Biochemistry, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, Pennsylvania 19104-6009, USA

Search for other papers by Rajat Kumar Das in
Google Scholar
PubMed Close
,
Sarmistha Banerjee Laboratories of Biochemistry, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, Pennsylvania 19104-6009, USA

Search for other papers by Sarmistha Banerjee in
Google Scholar
PubMed Close
, and
Bernard H Shapiro Laboratories of Biochemistry, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, Pennsylvania 19104-6009, USA

Search for other papers by Bernard H Shapiro in
Google Scholar
PubMed Close

hormone levels per se that are responsible for phenotypic sexual dimorphisms ranging from growth patterns to expression levels of hepatic enzymes ( Jansson et al . 1985 , Shapiro et al . 1995 ). In the rat, CYP responses to GH regulation are nearly as

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0255
Volume/Issue:
Volume 216: Issue 1
Free access
Yuefei Huang Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Yuefei Huang in
Google Scholar
PubMed Close
,
Pei Yee Ting Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Pei Yee Ting in
Google Scholar
PubMed Close
,
Tham M Yao Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Tham M Yao in
Google Scholar
PubMed Close
,
Tsuyoshi Homma Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Tsuyoshi Homma in
Google Scholar
PubMed Close
,
Danielle Brooks Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Danielle Brooks in
Google Scholar
PubMed Close
,
Isis Katayama Rangel Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Isis Katayama Rangel in
Google Scholar
PubMed Close
,
Gail K Adler Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Gail K Adler in
Google Scholar
PubMed Close
,
Jose R Romero Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Jose R Romero in
Google Scholar
PubMed Close
,
Jonathan S Williams Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Jonathan S Williams in
Google Scholar
PubMed Close
,
Luminita H Pojoga Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Luminita H Pojoga in
Google Scholar
PubMed Close
, and
Gordon H Williams Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Search for other papers by Gordon H Williams in
Google Scholar
PubMed Close

aldosterone effect. Sexual dimorphism has been documented previously for blood pressure levels and regulation ( Yong et al . 1993 , Himmelmann et al . 1994 ). In humans, hypertension is more common in young males than in premenopausal females; the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0247
Volume/Issue:
Volume 240: Issue 2
Free access
Lucas Monje Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, Casilla de Correo 242, 3000 Santa Fe, Argentina

Search for other papers by Lucas Monje in
Google Scholar
PubMed Close
,
Jorgelina Varayoud Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, Casilla de Correo 242, 3000 Santa Fe, Argentina

Search for other papers by Jorgelina Varayoud in
Google Scholar
PubMed Close
,
Enrique H Luque Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, Casilla de Correo 242, 3000 Santa Fe, Argentina

Search for other papers by Enrique H Luque in
Google Scholar
PubMed Close
, and
Jorge G Ramos Laboratorio de Endocrinología y Tumores Hormonodependientes, School of Biochemistry and Biological Sciences, Universidad Nacional del Litoral, Casilla de Correo 242, 3000 Santa Fe, Argentina

Search for other papers by Jorge G Ramos in
Google Scholar
PubMed Close

time point studied. At PND8, ERα 5′UTR variant expression in the POA showed a great sexual dimorphism, since control females showed higher levels of ERα-OT, ERα-O, and ERα-E1 transcripts than male pups ( P < 0.05, Fig. 4A–C ). DES

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0014
Volume/Issue:
Volume 194: Issue 1
Free access
T V Novoselova Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by T V Novoselova in
Google Scholar
PubMed Close
,
R Larder University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by R Larder in
Google Scholar
PubMed Close
,
D Rimmington University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by D Rimmington in
Google Scholar
PubMed Close
,
C Lelliott Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by C Lelliott in
Google Scholar
PubMed Close
,
E H Wynn Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by E H Wynn in
Google Scholar
PubMed Close
,
R J Gorrigan Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by R J Gorrigan in
Google Scholar
PubMed Close
,
P H Tate Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by P H Tate in
Google Scholar
PubMed Close
,
L Guasti Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by L Guasti in
Google Scholar
PubMed Close
,
The Sanger Mouse Genetics Project Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by The Sanger Mouse Genetics Project in
Google Scholar
PubMed Close
,
S O’Rahilly University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by S O’Rahilly in
Google Scholar
PubMed Close
,
A J L Clark Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by A J L Clark in
Google Scholar
PubMed Close
,
D W Logan Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Search for other papers by D W Logan in
Google Scholar
PubMed Close
,
A P Coll University of Cambridge Metabolic Research Laboratories, MRC Metabolic Disease Unit, Wellcome Trust-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

Search for other papers by A P Coll in
Google Scholar
PubMed Close
, and
L F Chan Centre for Endocrinology, Queen Mary University of London, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London, UK

Search for other papers by L F Chan in
Google Scholar
PubMed Close

either global P -values for genotype adjusted for multiple correction testing, or (in the cases of sexual dimorphism) the P -value is the impact of genotype for that sex. Animal husbandry The care and use of all animals were carried out in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0057
Volume/Issue:
Volume 230: Issue 1
Open access
Chandrika D Mahalingam Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Chandrika D Mahalingam in
Google Scholar
PubMed Close
,
Bharat Reddy Sampathi Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Bharat Reddy Sampathi in
Google Scholar
PubMed Close
,
Sonali Sharma Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Sonali Sharma in
Google Scholar
PubMed Close
,
Tanuka Datta Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Tanuka Datta in
Google Scholar
PubMed Close
,
Varsha Das Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Varsha Das in
Google Scholar
PubMed Close
,
Abdul B Abou-Samra Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Abdul B Abou-Samra in
Google Scholar
PubMed Close
, and
Nabanita S Datta Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA
Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA
Division of Endocrinology, Barbara Ann Karmanos Cancer Institute, Cardiovascular Research Institute, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA

Search for other papers by Nabanita S Datta in
Google Scholar
PubMed Close

and death in astrocytes and possibly contributes to sexual dimorphisms in brain development ( Zhang et al . 2002 ). MAPKs regulate cyclin D1 ( Terada et al . 1999 ), an unique regulator of cell cycle progression and cell proliferation ( Sherr

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0372
Volume/Issue:
Volume 216: Issue 3
Free access
Lianne Abrahams School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Lianne Abrahams in
Google Scholar
PubMed Close
,
Nina M Semjonous School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Nina M Semjonous in
Google Scholar
PubMed Close
,
Phil Guest School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Phil Guest in
Google Scholar
PubMed Close
,
Agnieszka Zielinska School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Agnieszka Zielinska in
Google Scholar
PubMed Close
,
Beverly Hughes School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Beverly Hughes in
Google Scholar
PubMed Close
,
Gareth G Lavery School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Gareth G Lavery in
Google Scholar
PubMed Close
, and
Paul M Stewart School of Clinical and Experimental Medicine, Institute of Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Search for other papers by Paul M Stewart in
Google Scholar
PubMed Close

, although the ultimate reason for the observed sexual dimorphism remains obscure. 11β-HSD1/H6PDH HETs and double HETs have a urinary 11-DHC profile that is comparable to that of WT animals ( Fig. 2 ). Loss of one 11β-HSD1 and/or one H6PDH allele therefore

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0178
Volume/Issue:
Volume 214: Issue 3
Open access
View license