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Eugenie Macfarlane Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia

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Hong Zhou Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia

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Markus J Seibel Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia
Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia

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by dynamic histomorphometry, whereas bone formation was unchanged in GR Runx2 treated mice. Importantly, the expression of Col1a1, a marker of osteoblast function, was significantly reduced after treatment with prednisolone in wild-type but not GR

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Wang Xiao Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Fei Beibei Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Shen Guangsi Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Jiang Yu Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Zhang Wen Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Huang Xi Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Xu Youjia Departments of Orthopaedics, Gynaecology, Department of Orthopaedic Research Institution, Department of Medicine, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, 215004 Suzhou, China

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Karnsombat P Choubtum L Sriphrapradang A Domrongkitchaiporn S Sirisriro R Rajatanavin R 2003 Bone histomorphometry in children and adolescents with β-thalassemia disease: iron-associated focal osteomalacia . Journal of Clinical Endocrinology

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Branka Šošić-Jurjević
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Branko Filipović
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Kostja Renko Department of Cytology, Institut für Experimentelle Endokrinologie, Institute for Biological Research ‘Siniša Stanković’, University of Belgrade, Despot Stefan Boulevard 142, 11000 Belgrade, Serbia

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Vladimir Ajdžanović
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Milica Manojlović-Stojanoski
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Verica Milošević
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Josef Köhrle Department of Cytology, Institut für Experimentelle Endokrinologie, Institute for Biological Research ‘Siniša Stanković’, University of Belgrade, Despot Stefan Boulevard 142, 11000 Belgrade, Serbia

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cells and bone histomorphometry in middle-aged rats . Histochemistry and Cell Biology 128 153 – 159 . ( doi:10.1007/s00418-007-0307-5 ) Gentry RT Wade GN 1976 Androgenic control of food intake and body weight in male rats . Journal of

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Corine Martineau
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Louise Martin-Falstrault Laboratoire du Métabolisme Osseux, Laboratoire du Métabolisme des Lipoprotéines, BioMed, Département des Sciences Biologiques Université du Québec à Montréal, Case Postale 8888, Succursale Centre-ville, Montréal, Quebec, Canada H3C 3P8

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Louise Brissette Laboratoire du Métabolisme Osseux, Laboratoire du Métabolisme des Lipoprotéines, BioMed, Département des Sciences Biologiques Université du Québec à Montréal, Case Postale 8888, Succursale Centre-ville, Montréal, Quebec, Canada H3C 3P8

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Robert Moreau
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atherosclerosis? Circulation 113 2548 – 2555 . ( doi:10.1161/CIRCULATIONAHA.104.475715 ) Erben RG 1997 Embedding of bone samples in methylmethacrylate: an improved method suitable for bone histomorphometry, histochemistry, and immunohistochemistry

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Marina Komrakova
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Carsten Werner Department of Trauma Surgery and Reconstructive Surgery, Institute of Animal Breeding and Genetics, Department of Endocrinology, University of Goettingen, Robert-Koch Strasse 40, 37075 Goettingen, Germany

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Michael Wicke Department of Trauma Surgery and Reconstructive Surgery, Institute of Animal Breeding and Genetics, Department of Endocrinology, University of Goettingen, Robert-Koch Strasse 40, 37075 Goettingen, Germany

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Ba Tiep Nguyen Department of Trauma Surgery and Reconstructive Surgery, Institute of Animal Breeding and Genetics, Department of Endocrinology, University of Goettingen, Robert-Koch Strasse 40, 37075 Goettingen, Germany

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Stephan Sehmisch
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Mohammad Tezval
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Klaus Michael Stuermer
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Ewa Klara Stuermer
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mitochondrial function . European Journal of Biochemistry 268 1422 – 1429 . Turner RT Vandersteenhoven JJ Bell NH 1987 The effects of ovariectomy and 17 beta-estradiol on cortical bone histomorphometry in growing rats . Journal of Bone and

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C D Simmons
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J M P Pabona
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Z Zeng
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M C Velarde
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D Gaddy
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F A Simmen
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R C M Simmen Department of Physiology and Biophysics, Arkansas Children's Nutrition Center, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, Arkansas 72202, USA

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histomorphometry, while the other horn was processed for RNA isolation. A total of 16 WT (9 and 7 respectively for Oil and DES) and 16 KO (8 and 8 respectively for Oil and DES) mice were used for tissue collection and analyses ( Fig. 1 ). Figure 1 Experimental

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Donlaporn Kittivanichkul Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand

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Narattaphol Charoenphandhu Center of Calcium and Bone Research (COCAB), Faculty of Science, Mahidol University, Bangkok, Thailand
Department of Physiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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Phisit Khemawoot Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

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Suchinda Malaivijitnond Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
National Primate Research Center of Thailand, Chulalongkorn University, Saraburi, Thailand

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histomorphometry in estrogen-deficient rats . Journal of Natural Medicines 70 225 – 233 . ( doi:10.1007/s11418-016-0965-5 ) Sweet MG Sweet JM Jeremiah MP Galazka SS 2009 Diagnosis and treatment of osteoporosis . American Family Physician

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Rocío Fuente Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland
Division of Pediatrics, University of Oviedo, Oviedo, Spain
Department of Pediatrics, Hospital Universitario Central, Oviedo, Spain

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Eva-Maria Pastor-Arroyo Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland

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Nicole Gehring Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland

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Patricia Oro Carbajosa Division of Pediatrics, University of Oviedo, Oviedo, Spain

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Laura Alonso-Durán Division of Pediatrics, University of Oviedo, Oviedo, Spain

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Ivan Zderic AO Research Institute Davos, AO Foundation, Clavadelerstrasse, Davos Platz, Switzerland

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James Tapia-Dean Department of Pediatrics, Hospital Universitario Central, Oviedo, Spain

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Ahmad Kamal Hamid Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland

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Carla Bettoni Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland

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Fernando Santos Division of Pediatrics, University of Oviedo, Oviedo, Spain
Department of Pediatrics, Hospital Universitario Central, Oviedo, Spain

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Carsten A Wagner Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland

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Isabel Rubio-Aliaga Institute of Physiology, University of Zurich, and National Center of Competence in Research NNCR Kidney, Zurich, CH, Switzerland

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). Histomorphometry and immunofluorescence After µCT analysis, the right tibia was fixed in 4% paraformaldehyde (PFA) and embedded in methyl methacrylate (MMA), as described previously ( Fuente et al. 2018 ). DAPI + DTAF staining in methacrylate sections was

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Alok Tripathi Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, 226031, India
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

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Pallavi Awasthi Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India
Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, 226031, India

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Kundan Singh Rawat Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India
Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, 226031, India

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Atma P Dwivedi Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, 226031, India

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Krishna Bhan Singh Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, 226031, India
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

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Kriti Sharma Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, 226031, India
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

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Ravi Prakash Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, 226031, India

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Divya Singh Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, 226031, India
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

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Atul Goel Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India
Division of Medicinal & Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, 226031, India

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thickness). Bone histomorphometry Bone histomorphometric assessment was performed by fluorochrome labeling experiment during the treatment regimen. Bone regeneration at the defect site was assessed by single calcein label after commencement of

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K David Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven
Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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V Dubois Basic and Translational Endocrinology, Department of Basic and Applied Medical Sciences, UGent, Ghent, Belgium

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A Verhulst Laboratory of Pathophysiology, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium

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V Sommers Molecular Endocrinology, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

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D Schollaert Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven

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L Deboel Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven

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K Moermans Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven

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G Carmeliet Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven

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P D’Haese Laboratory of Pathophysiology, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium

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D Vanderschueren Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven
Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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F Claessens Molecular Endocrinology, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

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P Evenepoel Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
Department of Nephrology, University Hospitals Leuven, Leuven, Belgium

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B Decallonne Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven
Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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( Ogirima et al. 2006 ). The bone phenotype as assessed by histomorphometry of the present adenine 0.25%/low vitamin K diet has been well described by Neven et al ( Neven et al. 2015 ). A typical hyperparathyroid bone disease with high turnover was

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