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Min Liu Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China

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Shuo Xie Department of Geriatric Medicine, Peking University First Hospital, Beijing, China

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Weiwei Liu Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China

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Jingjin Li Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China

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Chao Li Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China

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Wei Huang Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China

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Hexin Li Biological Sample Management Center, Beijing Hospital, Beijing, China

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Jinghai Song Department of Surgery, Beijing Hospital, Beijing, China

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Hong Zhang Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China

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Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPAR γ in radiation-induced fibrosis . Oncotarget 90579 – 90604 . ( https://doi.org/10.18632/oncotarget.21234 ) 29163854 Wang K Tang Z Zheng Z Cao P Shui W Li Q Zhang Y 2016

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0029
Volume/Issue:
Volume 244: Issue 1
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Dong-Xu Han Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Chang-Jiang Wang Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Xu-Lei Sun Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Jian-Bo Liu Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Hao Jiang Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Yan Gao Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Cheng-Zhen Chen Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Bao Yuan Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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Jia-Bao Zhang Department of Laboratory Animals, College of Animal Sciences, Jilin University, Changchun, Jilin, People’s Republic of China

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and reproduction in the pituitary, including the BMP, WNT, NOTCH, GnRH and thyroid hormone signaling pathways ( Ericson et al. 1998 , Raetzman et al. 2004 , Potok et al. 2008 , Li et al. 2017 ). However, information on pituitary circRNAs

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0540
Volume/Issue:
Volume 240: Issue 3
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Shi-Yan Li Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming 82071, USA

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Cindy X Fang Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming 82071, USA

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Nicholas S Aberle II Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming 82071, USA

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Bonnie H Ren Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming 82071, USA

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Asli F Ceylan-Isik Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming 82071, USA

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Jun Ren Division of Pharmaceutical Sciences and Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, Wyoming 82071, USA

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-12 rapamycin-associated protein, is considered a critical player for cell signaling pathways from translational machinery, cell growth and metabolism to survival/ apoptosis in many cell types including ventricular myocytes. Phosphorylation of mTOR may

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Research Article
DOI:
https://doi.org/10.1677/joe.1.06168
Volume/Issue:
Volume 186: Issue 3
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R C M Simmen Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

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J M P Pabona Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

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M C Velarde Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

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C Simmons Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

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O Rahal Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

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F A Simmen Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA

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progesterone receptor (PGR), in coordination with a whole host of functionally context-dependent coregulators to stimulate or inhibit target gene transcription. The signal transduction pathways initiated by the binding of E 2 and progesterone to their

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0329
Volume/Issue:
Volume 204: Issue 3
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Lingyun Lu Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China

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Li Tian Laboratory of Endocrinology and Metabolism, Department of Endocrinology, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China

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and from in vivo study demonstrated that the ability of osteocytes to activate the Wnt/β-catenin signaling pathway in response to mechanical loading was weakened significantly, which further strengthens evidence for the role of estrogen in the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-23-0116
Volume/Issue:
Volume 259: Issue 1
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Sanhua Leng
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Wenshuo Zhang
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Yanbin Zheng
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Ziva Liberman The Section of Endocrinology, The University of Chicago, The Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, KCBD Room 8122, 900 East 57th Street, Chicago, Illinois 60637, USA

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Christopher J Rhodes
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Hagit Eldar-Finkelman The Section of Endocrinology, The University of Chicago, The Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, KCBD Room 8122, 900 East 57th Street, Chicago, Illinois 60637, USA

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Xiao Jian Sun
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. 1993 , White 2006 ). These interactions lead to the activation of multiple signaling pathways required for insulin's pleiotropic actions ( White 2006 ). In addition, IRS1 also contains multiple serine/threonine phosphorylation sites ( Sun et al . 1991

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0456
Volume/Issue:
Volume 206: Issue 2
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Shuai Li School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA

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Wipawee Winuthayanon School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA

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phenotypes lead to degeneration of the eggs and embryo transport failure. WNT7a is another critical signaling pathway involved in early female reproductive tract development, as a loss of Wnt7a results in female sterility due to an abnormal development of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0302
Volume/Issue:
Volume 232: Issue 1
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Débora Cristina de Moraes
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Mario Vaisman Laboratório de Endocrinologia Molecular, Hospital Universitário Clementino Fraga Filho, Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Rio de Janeiro CEP 21949-900, Brasil

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Flavia Lucia Conceição Laboratório de Endocrinologia Molecular, Hospital Universitário Clementino Fraga Filho, Instituto de Biofísica Carlos Chagas Filho, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Rio de Janeiro CEP 21949-900, Brasil

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Tânia Maria Ortiga-Carvalho
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(FGF; Ericson et al . 1998 ) and wingless (WNT) pathways ( Rizzoti & Lovell-Badge 2005 ). Figure 1 Early pituitary development. The most anterior portion of the neural plate gives rise to the anterior pituitary and the adjacent midline region forms

Article Type:
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DOI:
https://doi.org/10.1530/JOE-12-0229
Volume/Issue:
Volume 215: Issue 2
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Kelly D McCall Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Dawn Holliday Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Eric Dickerson Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Brian Wallace Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Anthony L Schwartz Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Christopher Schwartz Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Christopher J Lewis Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Leonard D Kohn Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Frank L Schwartz Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center

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Introduction The activation of inflammatory pathways in adipose and other tissues is an important mediator of obesity-related insulin resistance ( Kahn & Flier 2000 , Lau et al . 2005 ). In obesity and type 2 diabetes mellitus (T2DM), visceral

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0370
Volume/Issue:
Volume 207: Issue 3
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Katherine A Staines The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Edinburgh, Midlothian EH25 9RG, UK

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Vicky E MacRae The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Edinburgh, Midlothian EH25 9RG, UK

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Colin Farquharson The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Edinburgh, Midlothian EH25 9RG, UK

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G Kim GS Ryoo HM 2011 Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression

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Research Article
DOI:
https://doi.org/10.1530/JOE-12-0143
Volume/Issue:
Volume 214: Issue 3
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