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Interactions between TGF-β1, canonical WNT/β-catenin pathway and PPAR γ in radiation-induced fibrosis . Oncotarget 90579 – 90604 . ( https://doi.org/10.18632/oncotarget.21234 ) 29163854 Wang K Tang Z Zheng Z Cao P Shui W Li Q Zhang Y 2016
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and reproduction in the pituitary, including the BMP, WNT, NOTCH, GnRH and thyroid hormone signaling pathways ( Ericson et al. 1998 , Raetzman et al. 2004 , Potok et al. 2008 , Li et al. 2017 ). However, information on pituitary circRNAs
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-12 rapamycin-associated protein, is considered a critical player for cell signaling pathways from translational machinery, cell growth and metabolism to survival/ apoptosis in many cell types including ventricular myocytes. Phosphorylation of mTOR may
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
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Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
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Department of Physiology and Biophysics, Interdisciplinary Biomedical Sciences Program, Arkansas Children's Nutrition Center, Buck Institute for Age Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, Arkansas 72202, USA
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progesterone receptor (PGR), in coordination with a whole host of functionally context-dependent coregulators to stimulate or inhibit target gene transcription. The signal transduction pathways initiated by the binding of E 2 and progesterone to their
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and from in vivo study demonstrated that the ability of osteocytes to activate the Wnt/β-catenin signaling pathway in response to mechanical loading was weakened significantly, which further strengthens evidence for the role of estrogen in the
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. 1993 , White 2006 ). These interactions lead to the activation of multiple signaling pathways required for insulin's pleiotropic actions ( White 2006 ). In addition, IRS1 also contains multiple serine/threonine phosphorylation sites ( Sun et al . 1991
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phenotypes lead to degeneration of the eggs and embryo transport failure. WNT7a is another critical signaling pathway involved in early female reproductive tract development, as a loss of Wnt7a results in female sterility due to an abnormal development of
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(FGF; Ericson et al . 1998 ) and wingless (WNT) pathways ( Rizzoti & Lovell-Badge 2005 ). Figure 1 Early pituitary development. The most anterior portion of the neural plate gives rise to the anterior pituitary and the adjacent midline region forms
Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
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Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
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Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
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Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
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Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
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Department of Specialty Medicine, Appalachian Rural Health Institute, Edison Biotechnology Institute, Department of Biomedical Sciences, Biomedical Engineering Program, Interthyr Corporation, Diabetes Research Center
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Introduction The activation of inflammatory pathways in adipose and other tissues is an important mediator of obesity-related insulin resistance ( Kahn & Flier 2000 , Lau et al . 2005 ). In obesity and type 2 diabetes mellitus (T2DM), visceral
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G Kim GS Ryoo HM 2011 Wnt3a stimulates Mepe, matrix extracellular phosphoglycoprotein, expression directly by the activation of the canonical Wnt signaling pathway and indirectly through the stimulation of autocrine Bmp-2 expression