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Department of Biochemistry (U38-FCT), School of Biotechnology, Faculty of Nutrition and Food Sciences, Animal Facility, Department of Clinical Pathology, ISPUP-EPIUnit, CINTESIS – Center for Research in Health Technologies and Information Systems, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
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Department of Biochemistry (U38-FCT), School of Biotechnology, Faculty of Nutrition and Food Sciences, Animal Facility, Department of Clinical Pathology, ISPUP-EPIUnit, CINTESIS – Center for Research in Health Technologies and Information Systems, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
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Department of Biochemistry (U38-FCT), School of Biotechnology, Faculty of Nutrition and Food Sciences, Animal Facility, Department of Clinical Pathology, ISPUP-EPIUnit, CINTESIS – Center for Research in Health Technologies and Information Systems, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
Department of Biochemistry (U38-FCT), School of Biotechnology, Faculty of Nutrition and Food Sciences, Animal Facility, Department of Clinical Pathology, ISPUP-EPIUnit, CINTESIS – Center for Research in Health Technologies and Information Systems, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
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Department of Biochemistry (U38-FCT), School of Biotechnology, Faculty of Nutrition and Food Sciences, Animal Facility, Department of Clinical Pathology, ISPUP-EPIUnit, CINTESIS – Center for Research in Health Technologies and Information Systems, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
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perigestational period result in fetal programing of metabolic dysfunction during post-natal life? To address this central question, we studied the effect of a perigestational supplementation of the diet of Sprague–Dawley (SD) female rats with high levels of FA on
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Andrology Laboratory, ANZAC Research Institute, University of Sydney, Concord Hospital, Sydney, New South Wales, Australia
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Laboratory for Ageing Research, School of Medical Sciences, University of New South Wales Sydney, New South Wales, Australia
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Andrology Laboratory, ANZAC Research Institute, University of Sydney, Concord Hospital, Sydney, New South Wales, Australia
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5alpha-dihydrotestosterone in intact and ovariectomized immature female rats . Biology of Reproduction 15 107 – 114 . ( https://doi.org/10.1095/biolreprod15.1.107 ) Azziz R Carmina E Dewailly D Diamanti-Kandarakis E Escobar
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Department of Endocrinology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK
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facilitates a range of reproductive behaviours, which act as important precursors to reproduction. In non-primate female mammals, male tactile stimuli lead to the female adopting a lordosis posture, crucial for reproductive success, characterised by ventral
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Division of Endocrinology and Metabolism, Center for Human Reproduction, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, PO Box 693, Rochester, New York 14642, USA
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–pituitary axis or metabolic tissues. The development of the global AR knockout (ARKO) female mouse models in the mid- and late 2000 established the importance of direct androgen action through ARs in normal female reproduction. The first Ar -null model ( Lyon
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Introduction Insulin-like growth factor I (IGF-I) plays a central role in the complex system that regulates growth, differentiation, and reproduction. It selectively promotes mitogenesis and differentiation and inhibits apoptosis ( Jones & Clemmons
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-opiomelanocortin ( Pomc ) mRNA levels. Materials and methods Animals and experimental design Female Wistar rats (10 weeks old) were used for breeding. Pregnancy was determined by vaginal smears and pregnant animals were randomly assigned into either the control or the BPA
Department of Biological Sciences, Lock Haven University, Lock Haven, Pennsylvania 17745, USA
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Department of Biological Sciences, Lock Haven University, Lock Haven, Pennsylvania 17745, USA
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Department of Biological Sciences, Lock Haven University, Lock Haven, Pennsylvania 17745, USA
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Department of Biological Sciences, Lock Haven University, Lock Haven, Pennsylvania 17745, USA
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Department of Biological Sciences, Lock Haven University, Lock Haven, Pennsylvania 17745, USA
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ovariectomized female rodents restores to normal the hypothalamic levels of GnRH mRNA ( Zoeller & Young 1988 , Zoeller et al. 1988 ), GnRH content ( Wise et al. 1981 a ), and GnRH secretion ( Wise & Ratner 1980 , Wise et al. 1981 b ). However, in vitro
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JL, Weigle DS, Clifton DK & Steiner RA 1997 Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology 138 855 –858. Clarke IJ & Henry BA 1999 Leptin and reproduction. Reviews in
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DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Göttingen, Germany
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DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Göttingen, Germany
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DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Göttingen, Germany
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reproductive life. However, the reproductive axis performance in adults is sensitive to the current nutritional status of the body, environmental cues and the systemic steroid milieu in both male and female ( Winter et al. 1987 , Clarke & Caraty 2013
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concentrations in infantile female mice . Journal of Reproduction and Fertility 43 189 – 192 . ( https://doi.org/10.1530/jrf.0.0430189 ) 10.1530/jrf.0.0430189 1127637 Durlinger AL Gruijters MJ Kramer P Karels B Kumar TR Matzuk MM Rose UM de Jong FH