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Eriko Inoue Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Toshihiro Ichiki Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Kotaro Takeda Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Hirohide Matsuura Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Toru Hashimoto Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Jiro Ikeda Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Aya Kamiharaguchi Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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Kenji Sunagawa Departments of, Cardiovascular Medicine, Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

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( Shoelson et al . 2006 ). These cytokines, so-called adipokines, cause inflammation and recruitment of macrophages to adipose tissue ( Xu et al . 2003 ), which is another important mechanism for obesity-induced insulin resistance. The infiltrated

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0014
Volume/Issue:
Volume 213: Issue 3
Free access
Junlan Zhou
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Min Cheng Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Chan Boriboun
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Mariam M Ardehali
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Changfei Jiang Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Qinghua Liu Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Shuling Han
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David A Goukassian Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Yao-Liang Tang Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Ting C Zhao Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Ming Zhao
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Lu Cai Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Stéphane Richard Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Raj Kishore Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Gangjian Qin
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various immune cells ( Osborn & Olefsky 2012 ). More recently, studies have shown that adipose tissue macrophages derived from lean mice express markers of M2, or ‘alternative activated’, macrophages. In contrast, obese states are concomitant with M1, or

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0727
Volume/Issue:
Volume 225: Issue 3
Free access
Yanqiu Wang Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Zhou Jin Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Jiajun Sun Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Xinxin Chen Department of Endocrine and Metabolic Diseases, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Shanghai, China

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Pu Xie Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yulin Zhou Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Shu Wang Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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, a CD14 + monocyte/macrophage-restricted receptor and an interferon-stimulated gene (ISG) that is upregulated by type I IFN, was increased in uGD patients at both the monocyte mRNA and serum levels. Inhibiting monocyte SIGLEC1 expression caused

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0453
Volume/Issue:
Volume 255: Issue 1
Free access
Farhana Naznin Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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Koji Toshinai Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan
Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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T M Zaved Waise Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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Cherl NamKoong Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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Abu Saleh Md Moin Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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Hideyuki Sakoda Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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Masamitsu Nakazato Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan
Division of Neurology, Department of Sports and Fitness, AMED-CREST, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

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12 weeks. Expression of the ghrelin receptor in both the nodose ganglion and hypothalamus were downregulated in HFD-fed mice. We also investigated inflammation in the nodose ganglion and hypothalamus by performing immunohistochemistry of macrophages

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0139
Volume/Issue:
Volume 226: Issue 1
Open access
K Vagnerová Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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M Kverka Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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P Klusoňová Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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P Ergang Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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I Mikšík Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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H Tlaskalová-Hogenová Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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J Pácha Institutes of Physiology and
Microbiology, Czech Academy of Sciences, Vídenská 1083, CZ-142 20 Prague 4, Czech Republic

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localized in the cells of lamina propria ( Whorwood et al. 1994 ). This matches with the findings of 11HSD1 in fibroblasts ( Hammami & Siiteri 1991 ), macrophages ( Thieringer et al. 2001 ), and lymphocytes ( Zhang et al. 2005 ). Consistent with the

Article Type:
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DOI:
https://doi.org/10.1677/joe.1.06732
Volume/Issue:
Volume 191: Issue 2
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Jessica R Mader
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Zachary T Resch
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Gary R McLean Endocrine Research Unit, Department of Comparative Medicine, Cellular and Molecular Immunology Research Centre, Department of Molecular Biology and Genetics, Division of Endocrinology, Mayo Clinic, 200 First Street SW, 5-194 Joseph, Rochester, Minnesota 55905, USA

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Jakob H Mikkelsen Endocrine Research Unit, Department of Comparative Medicine, Cellular and Molecular Immunology Research Centre, Department of Molecular Biology and Genetics, Division of Endocrinology, Mayo Clinic, 200 First Street SW, 5-194 Joseph, Rochester, Minnesota 55905, USA

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Claus Oxvig Endocrine Research Unit, Department of Comparative Medicine, Cellular and Molecular Immunology Research Centre, Department of Molecular Biology and Genetics, Division of Endocrinology, Mayo Clinic, 200 First Street SW, 5-194 Joseph, Rochester, Minnesota 55905, USA

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Ronald J Marler Endocrine Research Unit, Department of Comparative Medicine, Cellular and Molecular Immunology Research Centre, Department of Molecular Biology and Genetics, Division of Endocrinology, Mayo Clinic, 200 First Street SW, 5-194 Joseph, Rochester, Minnesota 55905, USA

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Cheryl A Conover
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mice. b Significant difference between 18-month-old non-diabetic and diabetic WT mice. Immunohistochemistry De-paraffinized sections of mouse kidney were stained for macrophages using F4/80 as primary antibody. Slides were rinsed with Tris

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0167
Volume/Issue:
Volume 219: Issue 1
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Zhongyang Lu Ralph H. Johnson Veterans Affairs Medical Center, Division of Endocrinology, Charleston, South Carolina 29401, USA

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Xiaoming Zhang Ralph H. Johnson Veterans Affairs Medical Center, Division of Endocrinology, Charleston, South Carolina 29401, USA

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Yanchun Li Ralph H. Johnson Veterans Affairs Medical Center, Division of Endocrinology, Charleston, South Carolina 29401, USA

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Junfei Jin Ralph H. Johnson Veterans Affairs Medical Center, Division of Endocrinology, Charleston, South Carolina 29401, USA

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Yan Huang Ralph H. Johnson Veterans Affairs Medical Center, Division of Endocrinology, Charleston, South Carolina 29401, USA
Ralph H. Johnson Veterans Affairs Medical Center, Division of Endocrinology, Charleston, South Carolina 29401, USA

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by endogenous ligands that are likely to be related to hyperlipidemia in Apoe −/− mice. Indeed, in vitro studies have shown that minimally modified LDL (mmLDL) is capable of inducing inflammatory cytokine production in macrophages by engaging TLR4

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DOI:
https://doi.org/10.1530/JOE-12-0338
Volume/Issue:
Volume 216: Issue 1
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Sébastien Desarzens Institute of Anatomy, University of Zurich, Zurich, Switzerland

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Nourdine Faresse Institute of Anatomy, University of Zurich, Zurich, Switzerland
Zurich Center of Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland
National Center of Competence in Research ‘Kidney.CH’, Zurich, Switzerland

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-inflammatory genes and macrophage infiltration into adipose tissue in obese mice ( Guo et al . 2008 , Hirata et al . 2009 , Lee et al . 2014 ). Conversely, selective activation of GR by dexamethasone decreases pro-inflammatory cytokine expression and macrophage

Article Type:
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DOI:
https://doi.org/10.1530/JOE-16-0121
Volume/Issue:
Volume 230: Issue 1
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Zhiguo Liu Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Chun Yan Lim Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Michelle Yu-Fah Su Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Stephanie Li Ying Soh Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Guanghou Shui Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Markus R Wenk Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Kevin L Grove Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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George K Radda Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Weiping Han Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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Xiaoqiu Xiao Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China

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local increases in the production of non-esterified fatty acids (NEFA). Through increased expression of pro-inflammatory cytokines and chemokines, and infiltration of macrophages and other immune cells into adipose tissue, obesity-induced inflammation is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0111
Volume/Issue:
Volume 219: Issue 2
Free access
Kayo Mori Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
Department of Cell Biology, Aging Science, and Pharmacology, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, Higashi-ku, Fukuoka, Japan
Section of Implant and Rehabilitative Dentistry, Division of Oral Rehabilitation, Kyushu University, Higashi-ku, Fukuoka, Japan

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Akiko Mizokami Oral Health/Brain Health/Total Health Research Center, Kyushu University, Higashi-ku, Fukuoka, Japan

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Tomomi Sano Department of Cell Biology, Aging Science, and Pharmacology, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, Higashi-ku, Fukuoka, Japan

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Satoru Mukai Department of Health and Nutrition Care, Faculty of Allied Health Sciences, University of East Asia, Shimonoseki, Japan

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Fumitaka Hiura Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan

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Yasunori Ayukawa Section of Implant and Rehabilitative Dentistry, Division of Oral Rehabilitation, Kyushu University, Higashi-ku, Fukuoka, Japan

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Kiyoshi Koyano Division of Advanced Dental Devices and Therapeutics, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

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Takashi Kanematsu Department of Cell Biology, Aging Science, and Pharmacology, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, Higashi-ku, Fukuoka, Japan

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Eijiro Jimi Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
Oral Health/Brain Health/Total Health Research Center, Kyushu University, Higashi-ku, Fukuoka, Japan

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significance was set at P < 0.05. Results Prolonged RANKL stimulation induces Tnfa expression via the non-canonical NF-κB pathway in BMCs Adipose tissue macrophages, some recruited from bone marrow-derived macrophages, contribute to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0424
Volume/Issue:
Volume 254: Issue 1
Restricted access