( Dirkx et al. 2012 ). These findings suggest a broader role for PKD in the control of glucose metabolism in various tissues. The liver is critical for the control of systemic glycemia and glucose metabolism. Under pre-prandial and fasting conditions
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Amanda J Genders, Timothy Connor, Shona Morrison, Simon T Bond, Brian G Drew, Peter J Meikle, Kirsten F Howlett, and Sean L McGee
Eloise A Bradley, Dino Premilovac, Andrew C Betik, Donghua Hu, Emily Attrill, Stephen M Richards, Stephen Rattigan, and Michelle A Keske
hour light/darkness cycle. Surgical procedure Rats fasted overnight (no food or metformin) and were anesthetised with an intraperitoneal injection of pentobarbital sodium (50 mg/kg body wt.). Complete surgical details are described previously
Monique C Saleh, Michael B Wheeler, and Catherine B Chan
and 16 weeks of age. Insulin tolerance tests were performed after a 4 h fast, as described ( Zhang et al. 2001 ) in ob/ob mice from all age groups. Lean mice from the 16-week age group served as controls. In a second group of overnight-fasted mice
Muhammad Furqan Bari, Sherry Ngo, Claire C Bastie, Allan M Sheppard, and Manu Vatish
splicing. We also found increased expression of multiple splice variants of the ubiquitin-conjugating enzymes UBE2D3 , and UBE2V1 variant 4 , in GDM. The expression of these genes was significantly associated with maternal fasting plasma glucose
Ashley Gray, William J Aronson, R James Barnard, Hemal Mehta, Junxiang Wan, Jonathan Said, Pinchas Cohen, and Colette Galet
( Yki-Jarvinen et al . 1995 , Katz et al . 1998 ). Fasting sera measurements from men (age 60±3 years) that participated in an 11-day low-fat diet and exercise program were found to have a 20% reduction in IGF1 levels, 53% increase in IGFBP1 levels
Bishnu Adhikari, Prabhat Khanal, and Mette Olaf Nielsen
kg MBW. The glucose tolerance test was conducted in the morning after the lambs had been fasted overnight. One propionate tolerance test was conducted approximately 4 h after the morning feeding, and the other was conducted after the lambs had been
Beatriz S Amorim, Cintia B Ueta, Beatriz C G Freitas, Renata J Nassif, Cecília Helena de Azevedo Gouveia, Marcelo A Christoffolete, Anselmo S Moriscot, Carmen Lucia Lancelloti, Flávia Llimona, Hermes Vieira Barbeiro, Heraldo Possolo de Souza, Sergio Catanozi, Marisa Passarelli, Marcelo S Aoki, Antonio C Bianco, and Miriam O Ribeiro
analyzed by the Sable Systems software. The results are expressed as milliliters of O 2 /min per g BW. Glucose tolerance test Animals were fasted overnight, and glucose (2 g/kg) was administered by i.p. injection between 0900 and 1000 h. Blood samples were
Ruben Rodriguez, Jacqueline N Minas, Jose Pablo Vazquez-Medina, Daisuke Nakano, David G Parkes, Akira Nishiyama, and Rudy M Ortiz
). Moreover, in individuals without CVD, but with impaired fasting glucose or glucose intolerance, treatment with an ACEi increased the regression to normoglycemia ( Bosch et al . 2006 ), suggesting that the state of the disease at the onset of RAS inhibition
Xiaoqin Shi, Xinyu Li, Yi Hou, Xuemei Cao, Yuyao Zhang, Heng Wang, Hongyin Wang, Chuan Peng, Jibin Li, Qifu Li, Chaodong Wu, and Xiaoqiu Xiao
paternal HFD ( Mitchell et al . 2011 ), low protein diet feeding ( Carone et al . 2010 ) or preconceptional fasting ( Anderson et al . 2006 ), metabolic profiles of offspring are significantly altered including hepatic lipid metabolism and pancreatic β
Bethany P Cummings, Ahmed Bettaieb, James L Graham, Kimber Stanhope, Fawaz G Haj, and Peter J Havel
throughout the study. Food intake and body weight (BW) were measured three times a week. Non-fasting blood glucose was monitored every week with a glucose meter (One-Touch Ultra, LifeScan, Milpitas, CA, USA) at 1300–1400 h using a lancet to collect a drop of