Search Results
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Inga K Johnsen in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Marc Slawik in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Igor Shapiro in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Michaela F Hartmann in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Stefan A Wudy in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Brendan D Looyenga in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Gary D Hammer in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Martin Reincke in
Google Scholar
PubMed
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Steroid Research Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University Giessen, Germany
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Medizinische Klinik - Innenstadt, Ludwig-Maximilians-University, Munich, Germany
Search for other papers by Felix Beuschlein in
Google Scholar
PubMed
factors such as GATA-4 ( P = 0.0005), Wilms tumor gene-1 (WT-1; P < 0.0001), and steriodogenic factor-1 (SF-1; P = 0.0029) were significantly up-regulated after GDX, while other transcription factors such as FOG-1 ( P < 0.0001) and GATA-6 ( P = 0
Search for other papers by B Shan in
Google Scholar
PubMed
Search for other papers by C Schaaf in
Google Scholar
PubMed
Search for other papers by A Schmidt in
Google Scholar
PubMed
Search for other papers by K Lucia in
Google Scholar
PubMed
Search for other papers by M Buchfelder in
Google Scholar
PubMed
Search for other papers by M Losa in
Google Scholar
PubMed
Search for other papers by D Kuhlen in
Google Scholar
PubMed
Search for other papers by J Kreutzer in
Google Scholar
PubMed
Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany
Search for other papers by M J Perone in
Google Scholar
PubMed
Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany
Search for other papers by E Arzt in
Google Scholar
PubMed
Search for other papers by G K Stalla in
Google Scholar
PubMed
Search for other papers by U Renner in
Google Scholar
PubMed
), the regulated subunit of the transcription factor HIF1 ( Harris 2002 , Hickey & Simon 2006 ). The latter is composed of two subunits, the constitutively expressed HIF1B and HIF1A, which is absent under normoxic conditions but is rapidly up
Instituto Bioingeniería, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Laboratorio de Medicina Regenerativa and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Universidad Miguel Hernández de Elche, Elche 03202, Alicante, Spain
Search for other papers by Ana B Ropero in
Google Scholar
PubMed
Instituto Bioingeniería, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Laboratorio de Medicina Regenerativa and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Universidad Miguel Hernández de Elche, Elche 03202, Alicante, Spain
Search for other papers by Pablo Juan-Picó in
Google Scholar
PubMed
Search for other papers by Alex Rafacho in
Google Scholar
PubMed
Instituto Bioingeniería, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Laboratorio de Medicina Regenerativa and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Universidad Miguel Hernández de Elche, Elche 03202, Alicante, Spain
Search for other papers by Esther Fuentes in
Google Scholar
PubMed
Search for other papers by F Javier Bermúdez-Silva in
Google Scholar
PubMed
Search for other papers by Enrique Roche in
Google Scholar
PubMed
Instituto Bioingeniería, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Laboratorio de Medicina Regenerativa and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Universidad Miguel Hernández de Elche, Elche 03202, Alicante, Spain
Search for other papers by Ivan Quesada in
Google Scholar
PubMed
Search for other papers by Fernando Rodríguez de Fonseca in
Google Scholar
PubMed
Instituto Bioingeniería, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Laboratorio de Medicina Regenerativa and CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Universidad Miguel Hernández de Elche, Elche 03202, Alicante, Spain
Search for other papers by Angel Nadal in
Google Scholar
PubMed
superfamily of ligand activated transcription factors ( Robinson-Rechavi et al . 2003 ). PPARs, particularly PPARα and γ, are regulators of lipid metabolism because they act as lipid sensors. Therefore, PPAR ligands represent important pharmaceutical agents
Search for other papers by L Bouraoui in
Google Scholar
PubMed
Search for other papers by J Gutiérrez in
Google Scholar
PubMed
Search for other papers by I Navarro in
Google Scholar
PubMed
(PPARγ) have been identified as transcriptional factors ( MacDougald & Lane 1995 ) and are necessary for the transition of pre-adipocytes into adipocytes in vitro . In mammals, insulin growth factor-I (IGF-I) affects adipocyte proliferation and
Search for other papers by Esther Dos Santos in
Google Scholar
PubMed
Search for other papers by Marie-Noëlle Dieudonné in
Google Scholar
PubMed
Search for other papers by Marie-Christine Leneveu in
Google Scholar
PubMed
Search for other papers by René Pecquery in
Google Scholar
PubMed
Search for other papers by Valérie Serazin in
Google Scholar
PubMed
Search for other papers by Yves Giudicelli in
Google Scholar
PubMed
the phospholipase A2 in the cytoplasm and several transcription factors in the nucleus like the proto-oncogene c-fos ( Janknecht et al. 1995 ), which plays a pivotal role in preadipocyte growth induction ( Lacasa et al. 1997 a , b ). The
Search for other papers by Masaya Takeda in
Google Scholar
PubMed
Search for other papers by Fumio Otsuka in
Google Scholar
PubMed
Search for other papers by Hiroyuki Otani in
Google Scholar
PubMed
Search for other papers by Kenichi Inagaki in
Google Scholar
PubMed
Search for other papers by Tomoko Miyoshi in
Google Scholar
PubMed
Search for other papers by Jiro Suzuki in
Google Scholar
PubMed
Search for other papers by Yukari Mimura in
Google Scholar
PubMed
Search for other papers by Toshio Ogura in
Google Scholar
PubMed
Search for other papers by Hirofumi Makino in
Google Scholar
PubMed
implicated it in processes of inflammation, atherosclerosis, cell cycle control, apoptosis, and carcinogenesis ( Auwerx 1999 ). PPARs act as a transcription factor when heterodimerized with the retinoid X receptor and bound to the proper ligands, including
Search for other papers by Lori Cole in
Google Scholar
PubMed
Search for other papers by Miranda Anderson in
Google Scholar
PubMed
Search for other papers by Parker B Antin in
Google Scholar
PubMed
Search for other papers by Sean W Limesand in
Google Scholar
PubMed
transcription factors involved in endocrine cell determination from pluripotent pancreatic progenitors has been established ( Jensen 2004 ). Using this knowledge, we determined PDX1 , NGN3 , and Nkx homeobox proteins, NKX2.2 and NKX6.1 , expression in sheep
Search for other papers by Aowen Zhuang in
Google Scholar
PubMed
Glycation and Diabetes Group, Mater Clinical School, Mater Research Institute - The University of Queensland, Translational Research Institute, 37 Kent Street, Woolloongabba, South Brisbane, Queensland, Australia
Search for other papers by Josephine M Forbes in
Google Scholar
PubMed
pathways, activated by transmembrane sensors located in the ER membrane. These three major pathways are the inositol-requiring protein 1 (IRE1), activating transcription factor 6 (ATF6) and the PKR-like ER kinase (PERK)-mediated response. When protein
Search for other papers by Eugenie Macfarlane in
Google Scholar
PubMed
Search for other papers by Hong Zhou in
Google Scholar
PubMed
Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia
Search for other papers by Markus J Seibel in
Google Scholar
PubMed
glucocorticoid receptor is a ligand-dependent transcription factor that mediates the diverse actions of glucocorticoids in nearly all tissues due to its ubiquitous expression in nucleated cells. The GR belongs to the nuclear receptor subfamily and has four
Key Laboratory of Transplant Engineering and Immunology, Department of Human Anatomy, Ministry of Health, Regenerative Medicine Research Center, West China Hospital, Sichuan University, No.1, Keyuan Road 4th, Wuhou District, Chengdu, Sichuan Province 610041, People's Republic of China
Search for other papers by Bo Chen in
Google Scholar
PubMed
Search for other papers by Yanrong Lu in
Google Scholar
PubMed
Search for other papers by Younan Chen in
Google Scholar
PubMed
Search for other papers by Jingqiu Cheng in
Google Scholar
PubMed
activity is disrupted, it is no longer possible to maintain appropriate redox balance. Nuclear factor-E2-related factor 2 (Nrf2), a transcription factor with a high sensitivity to oxidative stress, binds to antioxidant response elements (AREs) in the