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Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
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Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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in adipose tissue Cells of the lymphoid line represent a heterogenous cell population involved in both innate and acquired immunity. They develop in bone marrow, thymus and spleen ( Caspar-Bauguil et al. 2005 ). Blood lymphocytes are probably the
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estrone (E1), estradiol (17β-estradiol; E2), and estriol (E3) ( Fuentes & Silveyra 2019 ). Most estrogen is secreted by the ovaries ( Li & Wang 2018 , Mohamad et al. 2020 ); however, it is also produced by other tissues, such as adipose tissue, the
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protecting the body from pathogens, while tissue-resident macrophages are key players in tissue homeostasis and the resolution of inflammation. Monocytes are continuously replenished from the bone marrow, where they are derived from haematopoietic stem cells
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Neuroscience 17 387 – 399 . ( doi:10.1016/S0736-5748(99)00031-3 ) Devlin MJ Cloutier AM Thomas NA Panus DA Lotinun S Pinz I Baron R Rosen CJ Bouxsein ML 2010 Caloric restriction leads to high marrow adiposity and low bone mass in
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Osteoporosis and Physical Activity 5 210 . ( https://doi.org/10.4172/2329-9509.1000210 ) Keune JA Wong CP Branscum AJ Iwaniec UT Turner RT 2017 Bone marrow adipose tissue deficiency increases disuse-induced bone loss in male mice . Scientific
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Introduction White adipose tissue is a major endocrine organ, secreting a wide range of hormones and signaling factors ( Trayhurn & Beattie 2001 , Rajala & Scherer 2003 , Trayhurn & Wood 2004 , Rosen & Spiegelman 2006 ). The tissue is, in
Institute of Metabolism and Endocrinology, Department of Clinical Laboratory, Department of Orthopaedics, The Second Xiang-Ya Hospital of Central South University, 410011 ChangSha, People's Republic of China
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-activated protein kinase pathways to regulate cell differentiation, growth, and metabolism ( Cusi et al . 2000 ). The mammalian IRS family contains at least four members: ubiquitous IRS1 and IRS2, adipose tissue-predominant IRS3, and IRS4, which is expressed in the
Felsenstein Medical Research Center, Petach Tikva, Israel
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Felsenstein Medical Research Center, Petach Tikva, Israel
Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Felsenstein Medical Research Center, Petach Tikva, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Felsenstein Medical Research Center, Petach Tikva, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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. Aromatase catalyzes the rate-limiting step in the conversion of C19 androgens (androstenedione and testosterone) to C18 estrogenic steroids (estrone and estradiol). It is found in many tissues, including adipose tissue, brain, skin and bone ( Sasano et al
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Introduction Overweight and obesity are a major public health concern, with social and economic implications ( Finkelstein 2014 ). Both hypertrophy and hyperplasia of the adipose tissue, mainly in the visceral depot, are associated with high
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Introduction Chemerin, also known as retinoic acid receptor responder (tazarotene-induced) 2, is a hormone-like protein that is secreted by the liver and white adipose tissue (WAT) as well as at localized sites of inflammation ( Goralski et al