Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 81 - 90 of 1,070 items for :

  • Refine by access: All content x
Clear All
Mina Takahashi Medicine and Clinical Science, Departments of

Search for other papers by Mina Takahashi in
Google Scholar
PubMed Close
,
Fumio Otsuka Medicine and Clinical Science, Departments of

Search for other papers by Fumio Otsuka in
Google Scholar
PubMed Close
,
Tomoko Miyoshi Medicine and Clinical Science, Departments of

Search for other papers by Tomoko Miyoshi in
Google Scholar
PubMed Close
,
Hiroyuki Otani Medicine and Clinical Science, Departments of

Search for other papers by Hiroyuki Otani in
Google Scholar
PubMed Close
,
Junko Goto Medicine and Clinical Science, Departments of

Search for other papers by Junko Goto in
Google Scholar
PubMed Close
,
Misuzu Yamashita Medicine and Clinical Science, Departments of

Search for other papers by Misuzu Yamashita in
Google Scholar
PubMed Close
,
Toshio Ogura Medicine and Clinical Science, Departments of

Search for other papers by Toshio Ogura in
Google Scholar
PubMed Close
,
Hirofumi Makino Medicine and Clinical Science, Departments of

Search for other papers by Hirofumi Makino in
Google Scholar
PubMed Close
, and
Hiroyoshi Doihara Medicine and Clinical Science, Departments of

Search for other papers by Hiroyoshi Doihara in
Google Scholar
PubMed Close

Introduction The involvement of estrogen in the development and progression of breast cancer is well known ( Henderson et al . 1988 , Helzlsouer & Couzi 1995 , Colditz 1998 , Keen & Davidson 2003 ). Most premenopausal and postmenopausal breast

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0226
Volume/Issue:
Volume 199: Issue 3
Free access
Ebony T Gilbreath Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA
Department of Pathobiology, College of Veterinary Medicine, Tuskegee University, Tuskegee, Alabama, USA

Search for other papers by Ebony T Gilbreath in
Google Scholar
PubMed Close
,
Lakshmikripa Jaganathan Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA

Search for other papers by Lakshmikripa Jaganathan in
Google Scholar
PubMed Close
,
Madhan Subramanian Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA

Search for other papers by Madhan Subramanian in
Google Scholar
PubMed Close
,
Priya Balasubramanian Department of Pharmacology and Toxicology, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA

Search for other papers by Priya Balasubramanian in
Google Scholar
PubMed Close
,
Katrina D Linning Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA

Search for other papers by Katrina D Linning in
Google Scholar
PubMed Close
,
Sheba M J MohanKumar Department of Pharmacology and Toxicology, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA
Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

Search for other papers by Sheba M J MohanKumar in
Google Scholar
PubMed Close
, and
Puliyur S MohanKumar Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA
Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

Search for other papers by Puliyur S MohanKumar in
Google Scholar
PubMed Close

Background Chronic exposure to low levels of estrogen is known to accelerate reproductive aging in female rats ( Kasturi et al. 2009 ). In fact, during the normal aging process, female rats go through a period of constant estrous when they

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0274
Volume/Issue:
Volume 240: Issue 2
Free access
Koji Nagayama
Search for other papers by Koji Nagayama in
Google Scholar
PubMed Close
,
Shigekazu Sasaki
Search for other papers by Shigekazu Sasaki in
Google Scholar
PubMed Close
,
Akio Matsushita
Search for other papers by Akio Matsushita in
Google Scholar
PubMed Close
,
Kenji Ohba
Search for other papers by Kenji Ohba in
Google Scholar
PubMed Close
,
Hiroyuki Iwaki
Search for other papers by Hiroyuki Iwaki in
Google Scholar
PubMed Close
,
Hideyuki Matsunaga
Search for other papers by Hideyuki Matsunaga in
Google Scholar
PubMed Close
,
Shingo Suzuki
Search for other papers by Shingo Suzuki in
Google Scholar
PubMed Close
,
Hiroko Misawa
Search for other papers by Hiroko Misawa in
Google Scholar
PubMed Close
,
Keiko Ishizuka
Search for other papers by Keiko Ishizuka in
Google Scholar
PubMed Close
,
Yutaka Oki
Search for other papers by Yutaka Oki in
Google Scholar
PubMed Close
,
Jaeduk Yoshimura Noh Second Division, Ito Hospital, Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka 431-3192, Japan

Search for other papers by Jaeduk Yoshimura Noh in
Google Scholar
PubMed Close
, and
Hirotoshi Nakamura
Search for other papers by Hirotoshi Nakamura in
Google Scholar
PubMed Close

concentrations. However, administration of pharmacologic doses of estrogen (17-β-estradiol, E 2 ) was known to augment the effect of thyroid hormone replacement to suppress TSHβ and CGA mRNA ( Wondisford 1996 and references therein). Indeed, E 2 inhibits

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0128
Volume/Issue:
Volume 199: Issue 1
Free access
Sharon Maor Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Sharon Maor in
Google Scholar
PubMed Close
,
Doris Mayer Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Doris Mayer in
Google Scholar
PubMed Close
,
Ronit I Yarden Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Ronit I Yarden in
Google Scholar
PubMed Close
,
Adrian V Lee Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Adrian V Lee in
Google Scholar
PubMed Close
,
Rive Sarfstein Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Rive Sarfstein in
Google Scholar
PubMed Close
,
Haim Werner Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Haim Werner in
Google Scholar
PubMed Close
, and
Moshe Z Papa Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Group on Hormones and Signal Transduction, German Cancer Research Center, Heidelberg D-69120, Germany
Laboratory of Genomic Applications, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Oncological Surgery, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel

Search for other papers by Moshe Z Papa in
Google Scholar
PubMed Close

indicating that the biological activity of the IGF system is strongly associated with estrogen status ( Lee et al. 1999 , Yee & Lee 2000 ). Estrogens were shown to increase IGF-I binding and IGF-IR mRNA levels in MCF-7 cells by sevenfold, suggesting that

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.07016
Volume/Issue:
Volume 191: Issue 3
Free access
Lidia I Serova
Search for other papers by Lidia I Serova in
Google Scholar
PubMed Close
,
Heather A Harris Department of Biochemistry and Molecular Biology, Women's Health and Musculoskeletal Biology, New York Medical College, Valhalla, New York 10595, USA

Search for other papers by Heather A Harris in
Google Scholar
PubMed Close
,
Shreekrishna Maharjan
Search for other papers by Shreekrishna Maharjan in
Google Scholar
PubMed Close
, and
Esther L Sabban
Search for other papers by Esther L Sabban in
Google Scholar
PubMed Close

influencing these gender-related differences ( Walf & Frye 2005 , Scharfman & MacLusky 2008 , Stovall & Pinkentorn 2008 ). Estrogens have been found to modulate the functions of several physiological systems and their responses to stress in humans and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0029
Volume/Issue:
Volume 205: Issue 3
Free access
Susana I Sá Department of Biomedicine, Unit of Anatomy, Faculty of Medicine, University of Porto, Porto, Portugal
Faculty of Medicine, Center for Health Technology and Services Research (CINTESIS), University of Porto, Porto, Portugal

Search for other papers by Susana I Sá in
Google Scholar
PubMed Close
and
Bruno M Fonseca UCIBIO, REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal

Search for other papers by Bruno M Fonseca in
Google Scholar
PubMed Close

division of the VMN (VMNvl) expresses estrogen receptor (ER) a and b and progesterone receptors (PRs), which depend on the levels of their cognate ligands ( Lauber et al . 1990 , Shughrue et al . 1992 , Sá et al . 2013 , 2015 ). Earlier studies have

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0663
Volume/Issue:
Volume 233: Issue 2
Free access
Araceli Morales Laboratory of Cellular Neurobiology, Department of Physiology and
Laboratory of Animal Physiology, Department of Animal Biology, Institute of Biomedical Technologies, University of La Laguna, La Laguna, Spain

Search for other papers by Araceli Morales in
Google Scholar
PubMed Close
,
Miriam Gonzalez Laboratory of Cellular Neurobiology, Department of Physiology and
Laboratory of Animal Physiology, Department of Animal Biology, Institute of Biomedical Technologies, University of La Laguna, La Laguna, Spain

Search for other papers by Miriam Gonzalez in
Google Scholar
PubMed Close
,
Raquel Marin Laboratory of Cellular Neurobiology, Department of Physiology and
Laboratory of Animal Physiology, Department of Animal Biology, Institute of Biomedical Technologies, University of La Laguna, La Laguna, Spain

Search for other papers by Raquel Marin in
Google Scholar
PubMed Close
,
Mario Diaz Laboratory of Cellular Neurobiology, Department of Physiology and
Laboratory of Animal Physiology, Department of Animal Biology, Institute of Biomedical Technologies, University of La Laguna, La Laguna, Spain

Search for other papers by Mario Diaz in
Google Scholar
PubMed Close
, and
Rafael Alonso Laboratory of Cellular Neurobiology, Department of Physiology and
Laboratory of Animal Physiology, Department of Animal Biology, Institute of Biomedical Technologies, University of La Laguna, La Laguna, Spain

Search for other papers by Rafael Alonso in
Google Scholar
PubMed Close

GnRH neuronal network to transynaptically modulate the final output of GnRH into the median eminence ( Herbison 1998 , Herbison & Pape 2001 ). Estradiol (E 2 ), the main endogenous regulator of the hypothalamus–pituitary axis, acts through estrogen

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-06-0001
Volume/Issue:
Volume 194: Issue 1
Free access
Toni Welsh Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA
Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Toni Welsh in
Google Scholar
PubMed Close
,
Matrika Johnson Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Matrika Johnson in
Google Scholar
PubMed Close
,
Lijuan Yi Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Lijuan Yi in
Google Scholar
PubMed Close
,
Huiqing Tan Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Huiqing Tan in
Google Scholar
PubMed Close
,
Roksana Rahman Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Roksana Rahman in
Google Scholar
PubMed Close
,
Amy Merlino Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Amy Merlino in
Google Scholar
PubMed Close
,
Tamas Zakar Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA
Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Tamas Zakar in
Google Scholar
PubMed Close
, and
Sam Mesiano Department of Reproductive Biology, Mothers and Babies Research Centre, Department of Obstetrics and Gynaecology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA

Search for other papers by Sam Mesiano in
Google Scholar
PubMed Close

Introduction Estrogens (mainly estradiol (E 2 )) promote labor by stimulating biochemical and physical changes in myometrial cells that augment uterine contractility and excitability (for review, see Pepe & Albrecht (1995) ). Studies on various

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0358
Volume/Issue:
Volume 212: Issue 2
Free access
Mirja Rotinen Department of Health Sciences, Universidad Pública de Navarra, Avda. Barañain, 31008 Pamplona, Spain

Search for other papers by Mirja Rotinen in
Google Scholar
PubMed Close
,
Jon Celay Department of Health Sciences, Universidad Pública de Navarra, Avda. Barañain, 31008 Pamplona, Spain

Search for other papers by Jon Celay in
Google Scholar
PubMed Close
,
Marta M Alonso Department of Health Sciences, Universidad Pública de Navarra, Avda. Barañain, 31008 Pamplona, Spain

Search for other papers by Marta M Alonso in
Google Scholar
PubMed Close
,
Aranzazu Arrazola Department of Health Sciences, Universidad Pública de Navarra, Avda. Barañain, 31008 Pamplona, Spain

Search for other papers by Aranzazu Arrazola in
Google Scholar
PubMed Close
,
Ignacio Encio Department of Health Sciences, Universidad Pública de Navarra, Avda. Barañain, 31008 Pamplona, Spain

Search for other papers by Ignacio Encio in
Google Scholar
PubMed Close
, and
Joaquin Villar Department of Health Sciences, Universidad Pública de Navarra, Avda. Barañain, 31008 Pamplona, Spain

Search for other papers by Joaquin Villar in
Google Scholar
PubMed Close

Introduction The hydroxysteroid (17-beta) dehydrogenase (HSD17B) enzymes catalyze the oxidoreduction of hydroxyl/keto groups of androgens and estrogens and regulate intracellular availability of steroid hormones ( Mindnich et al . 2004 ). To date

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0134
Volume/Issue:
Volume 200: Issue 1
Free access
Patrick Müller Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Patrick Müller in
Google Scholar
PubMed Close
,
Kenneth W Merrell Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Kenneth W Merrell in
Google Scholar
PubMed Close
,
Justin D Crofts Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Justin D Crofts in
Google Scholar
PubMed Close
,
Caroline Rönnlund Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Caroline Rönnlund in
Google Scholar
PubMed Close
,
Chin-Yo Lin Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Chin-Yo Lin in
Google Scholar
PubMed Close
,
Jan-Åke Gustafsson Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Jan-Åke Gustafsson in
Google Scholar
PubMed Close
, and
Anders Ström Department of Biosciences and Nutrition, Department of Microbiology and Molecular Biology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden

Search for other papers by Anders Ström in
Google Scholar
PubMed Close

cells. This upregulation is important for the anti-estrogenic effect of atRA ( Muller et al . 2002 ) and appears to affect the expression of the cell cycle regulator E2F-1. Forced expression of HES-1 inhibits an E 2 -mediated increase in E2F-1 and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-08-0094
Volume/Issue:
Volume 200: Issue 3
Free access