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Department of Nephrology, The Second Hospital of Jilin University, Changchun, Jilin, People’s Republic of China
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Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, Jilin, People’s Republic of China
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2-related factor 2 (NRF2) has been identified as a governor of antioxidant and redox signaling. NRF2 activates the transcription of downstream antioxidant genes such as heme oxygenase-1 ( Ho1 ) and NAD(P)H dehydrogenase quinone 1 ( Nqo1 ) ( Ruiz et
Taichung Veterans General Hospital and Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
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Taichung Veterans General Hospital and Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
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Taichung Veterans General Hospital and Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
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Taichung Veterans General Hospital and Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
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signaling in cardiomyocytes will help elucidate how hormonal signaling modulates myocardial function. Insulin and IGF-I could prevent skeletal muscle cell atrophy and promote myogenesis through forkhead transcription factors (FOXO; Hribal et al
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which dominates circadian day: as noted above, the Clock delta19 mutation, which compromises transcriptional activation, lengthens circadian period in mice to ca. 28 h. Protein stability is another key factor ( Gallego & Virshup 2007 ). In the tau
Department of Zoology, University of Hong Kong, Hong Kong, China
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Department of Zoology, University of Hong Kong, Hong Kong, China
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Department of Zoology, University of Hong Kong, Hong Kong, China
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Department of Zoology, University of Hong Kong, Hong Kong, China
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immunohistochemistry (IHC) Genes with more than twofold change in their expression levels were tabulated and grouped by their general functions (Tables 3 –5 ). Among these are cytokines, transcription factors, kinases, phosphatases, genes that regulate ion
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transcription factor mandatory for differentia tion of satellite cells into muscle fibers ( te Pas et al . 2000 ). Catabolic action of glucocorticoids The stimulatory effect of glucocorticoids on muscle proteolysis results from the activation of the major
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Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany
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Neuroendocrinology Group, Department of Neurosurgery, Department of Neurosurgery, Department of Neurosurgery, Laboratorio de Fisiología y Biología Molecular, IBioBA–CONICET, Max Planck Institute of Psychiatry, Kraepelinstraße 10, D-80804 Munich, Germany
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), the regulated subunit of the transcription factor HIF1 ( Harris 2002 , Hickey & Simon 2006 ). The latter is composed of two subunits, the constitutively expressed HIF1B and HIF1A, which is absent under normoxic conditions but is rapidly up
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Physiology, Departments of
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a paired domain-containing transcription factor PAX8, and cAMP-response element-binding proteins, in response to the TSH/cAMP signal ( Taki et al . 2002 ). PI3K inhibition by LY294002 increases the binding of PAX8 to the NUE in PCCL3 rat thyroid
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transcription factors involved in endocrine cell determination from pluripotent pancreatic progenitors has been established ( Jensen 2004 ). Using this knowledge, we determined PDX1 , NGN3 , and Nkx homeobox proteins, NKX2.2 and NKX6.1 , expression in sheep
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Introduction Paired box (PAX) genes encode a family of transcription factors that are involved in the development of various tissues during early embryogenesis in vertebrates. They are known to possess paired domain and derived their name by
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transcriptional regulation by the hypoxia-inducible transcription factor, HIF-1 ( Grosfeld et al . 2001 , Ambrosini et al . 2002 ). The induction of leptin expression by hypoxia has also been reported in other cell types, including human trophoblast cell lines