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Masahiro Murakami
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Toshiya Matsuzaki
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Takeshi Iwasa
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Toshiyuki Yasui
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Minoru Irahara
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Tomohiro Osugi Department of Obstetrics and Gynecology, Department of Biology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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Kazuyoshi Tsutsui Department of Obstetrics and Gynecology, Department of Biology, The University of Tokushima Graduate School, Institute of Health Biosciences, 3-18-15 Kuramoto-Cho, Tokushima 770-8503, Japan

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. Journal of Neuroendocrinology 19 732 – 738 . Johnson MA Tsutsui K Fraley GS 2007 Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat . Hormones and

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Shabana Anjum
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Amitabh Krishna
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Kazuyoshi Tsutsui Department of Zoology, Department of Biology, Banaras Hindu University, Varanasi 221 005, Uttar Pradesh, India

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. Journal of Steroid Biochemistry 23 757 – 764 . ( doi:10.1016/S0022-4731(85)80011-X ) Johnson MA Tsutsui K Fraley GS 2007 Rat RFamide related peptide-3 stimulates GH secretion, inhibits LH secretion, and has a variable effect on sex behavior

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V Squicciarini Center for Neurobiochemical Studies in Endocrine Diseases, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Laboratory of Neurobiochemistry, Universidad de Chile, Santiago, Chile

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R Riquelme Center for Neurobiochemical Studies in Endocrine Diseases, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Laboratory of Neurobiochemistry, Universidad de Chile, Santiago, Chile

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K Wilsterman Department of Integrative Biology, UC Berkeley, Berkeley, California, USA

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G E Bentley Department of Integrative Biology, UC Berkeley, Berkeley, California, USA
Helen Wills Neuroscience Institute, UC Berkeley, Berkeley, California, USA

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H E Lara Center for Neurobiochemical Studies in Endocrine Diseases, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Laboratory of Neurobiochemistry, Universidad de Chile, Santiago, Chile

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the rat . Biology of Reproduction 68 2038 – 2043 . ( https://doi.org/10.1095/biolreprod.102.008318 ) 10.1095/biolreprod.102.008318 12606413 Ducret E Anderson GM Herbison AE 2009 RFamide-related peptide-3, a mammalian gonadotropin

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F Wahab Stem Cell Biology Unit, Laboratory of Reproductive Neuroendocrinology, Leibniz Institute for Primate Research, German Primate Center, Kellnerweg 4, D-37077 Göttingen, Germany

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M Shahab Stem Cell Biology Unit, Laboratory of Reproductive Neuroendocrinology, Leibniz Institute for Primate Research, German Primate Center, Kellnerweg 4, D-37077 Göttingen, Germany

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R Behr Stem Cell Biology Unit, Laboratory of Reproductive Neuroendocrinology, Leibniz Institute for Primate Research, German Primate Center, Kellnerweg 4, D-37077 Göttingen, Germany

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Investigation 121 355 – 368 . ( doi:10.1172/JCI45106 ) Ducret E Anderson GM Herbison AE 2009 RFamide-related peptide-3, a mammalian gonadotropin-inhibitory hormone ortholog, regulates gonadotropin-releasing hormone neuron firing in the mouse

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Fan Yang College of Bioengineering, Chongqing University, Chongqing, P. R. China

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Shuang Zhao College of Bioengineering, Chongqing University, Chongqing, P. R. China

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Pingqing Wang College of Bioengineering, Chongqing University, Chongqing, P. R. China

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Wei Xiang School of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing, P. R. China

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in Kiss1 neurons . Journal of Clinical Investigation 121 355 – 368 . ( https://doi.org/10.1172/JCI45106 ) Ducret E Anderson GM & Herbison AE 2009 RFamide-related Peptide-3, a mammalian gonadotropin-inhibitory hormone ortholog, regulates

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Jennifer A Yang Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, California, USA

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Jessica K Hughes Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, California, USA

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Ruby A Parra Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, California, USA

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Katrina M Volk Neuroscience Program, Washington and Lee University, Lexington, Virginia, USA

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Alexander S Kauffman Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Diego, La Jolla, California, USA

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GM Relf HL Rizwan MZ Evans JJ 2009 Central and peripheral effects of RFamide-related peptide-3 on luteinizing hormone and prolactin secretion in rats . Endocrinology 150 1834 – 1840 . ( https://doi.org/10.1210/en.2008-1359 ) 10.1210/en.2008

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M Moussavi Department of Biological Sciences, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4

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M Wlasichuk Department of Biological Sciences, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4
Department of Biological Sciences, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4

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J P Chang Department of Biological Sciences, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4
Department of Biological Sciences, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4

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H R Habibi Department of Biological Sciences, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4

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and Behavior 66 15 – 40 . ( doi:10.1016/j.yhbeh.2014.02.005 ) Clarke IJ Sari IP Qi Y Smith JT Parkington HC Ubuka T Iqbal J Li Q Tilbrook A Morgan K 2008 Potent action of RFamide-related peptide-3 on pituitary

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H Yin
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K Ukena
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T Ubuka
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K Tsutsui
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. Yoshida H , Habata Y, Hosoya M, Kawamata Y, Kitada C & Hinuma S 2003 Molecular properties of endogenous RFamide-related peptide-3 and its interaction with receptors. Biochimica et Biophysica Acta 1593 151 –157.

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Christopher J Scott School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia
Graham Centre for Agricultural Innovation, Wagga Wagga, New South Wales, Australia

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Jessica L Rose School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia
Graham Centre for Agricultural Innovation, Wagga Wagga, New South Wales, Australia

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Allan J Gunn Graham Centre for Agricultural Innovation, Wagga Wagga, New South Wales, Australia
School of Animal & Veterinary Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia

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Briony M McGrath School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia

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.114157 ) 24429215 Decourt C Anger K Robert V Lomet D Bartzen-Sprauer J Caraty A Dufourny L Anderson G Beltramo M 2015 No evidence that RFamide related peptide 3 directly modulates LH secretion in the ewe . Endocrinology 157 1566 – 1575 . ( https

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Sarika Paul Centre for Biological Timing, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK

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Timothy M Brown Centre for Biological Timing, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK

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GnRH neurons by supressing the activity of upstream inhibitory neurons in the DMH expressing RFamide-related peptide 3 ( Russo et al. 2015 ). Similarly, AVP-expressing SCN neurons provide a further indirect source of circadian control by exciting

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