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Jasleen Kaur Division of Endocrinology and Diabetes, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA

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Elizabeth R Seaquist Division of Endocrinology and Diabetes, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA

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activated in response to a fall in plasma glucose to a value less than 70 mg/dL ( Hawkes et al. 2019 ). Activation of the sympathetic nervous system, and cortisol and growth hormone secretion also occur as the glucose falls below 60–65 mg/dL ( Hawkes et

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