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Marion Régnier UCLouvain, Université Catholique de Louvain, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium

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Matthias Van Hul UCLouvain, Université Catholique de Louvain, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium

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Claude Knauf Université Paul Sabatier, Toulouse III, INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), CHU Purpan, Place du Docteur Baylac, Toulouse Cedex 3, France
European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium

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Patrice D Cani UCLouvain, Université Catholique de Louvain, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium
European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium

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metabolic abnormalities, prevention remains the greatest challenge. Among the different factors contributing to the regulation of energy balance, the microorganisms that reside in the human gut (called the gut microbiota) have received increasing attention

Article Type:
Review Article
Collections:
Gut microbiome special collection, Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-20-0473
Volume/Issue:
Volume 248: Issue 2
Free access
Fabio Arturo Iannotti Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Pozzuoli, Campania, Italy

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Vincenzo Di Marzo Director, Joint International Research Unit for the Chemical and Biomolecular Study of the Microbiome in Metabolic Health and Nutrition (JIRU-MicroMeNu) between the Consiglio Nazionale delle Ricerche (CNR, Institute of Biomolecular Chemistry) and Université Laval, Naples, Campania, Italy
Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada

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/time-dependent actions on lipid and glucose metabolism. In fact, unlike CB1, most other eCBome receptors negatively affect energy balance and play beneficial roles during metabolic disorders ( Fig. 2 ). In particular: (1) CB2 seems to reduce insulin resistance and hence

Article Type:
Review Article
Collections:
Gut microbiome special collection
DOI:
https://doi.org/10.1530/JOE-20-0444
Volume/Issue:
Volume 248: Issue 2
Free access
Nicole G Barra Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Fernando F Anhê Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Joseph F Cavallari Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Anita M Singh Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Darryl Y Chan Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Jonathan D Schertzer Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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digestion and intestinal absorption of dietary components and energy content is a key mechanism by which bacteria influence energy balance ( Bäckhed et al. 2004 ). Metabolic disease states, like obesity, can alter the gut microbiota to promote more energy

Article Type:
Review Article
Collections:
Gut microbiome special collection, Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-21-0081
Volume/Issue:
Volume 250: Issue 2
Free access