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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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linking sleep duration to obesity and T2DM. There are multiple plausible mechanisms that lead to changes to energy balance, beta cell function and insulin resistance ( Fig. 1 ). Figure 1 The mechanisms between short sleep duration and type 2
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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metabolic abnormalities, prevention remains the greatest challenge. Among the different factors contributing to the regulation of energy balance, the microorganisms that reside in the human gut (called the gut microbiota) have received increasing attention
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overexpression affected energy balance. Recombinant adenovirus (Ad-Asprosin) were generated and locally injected into the groin subcutaneous white adipose tissue to elevate the level of asprosin in vivo (Supplementary Fig. 1B, C and D). The whole-body oxygen
The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
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Animal Core Facility, Nanjing Medical University, Nanjing, Jiangsu, China
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. ( https://doi.org/10.1016/j.fertnstert.2008.11.025 ) Roa J Tena-Sempere M 2010 Energy balance and puberty onset: emerging role of central mTOR signaling . Trends in Endocrinology and Metabolism 21 519 – 528 . ( https://doi.org/10.1016/j
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digestion and intestinal absorption of dietary components and energy content is a key mechanism by which bacteria influence energy balance ( Bäckhed et al. 2004 ). Metabolic disease states, like obesity, can alter the gut microbiota to promote more energy