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Andre Sarmento-Cabral Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Mercedes del Rio-Moreno Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Mari C Vazquez-Borrego Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Mariyah Mahmood Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Elena Gutierrez-Casado Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Natalie Pelke Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Grace Guzman Department of Pathology, University of Illinois at Chicago, College of Medicine, Chicago, Illinois, USA

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Papasani V Subbaiah Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Jose Cordoba-Chacon Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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Shoshana Yakar Department of Molecular Pathobiology, New York University College of Dentistry, New York, New York, USA

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Rhonda D Kineman Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago and Research and Development Division, Jesse Brown VA Medical Center, Chicago, Illinois, USA

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lobe was fixed in 10% formalin and stored in 70% ethanol for histologic assessment. Commercial kits were used to determine plasma GH (EZRMGH-45K, Millipore Sigma, Burlington, MA), insulin (10-1247-01, Mercodia, Uppsala, Sweden) and IGF binding protein

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