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Julie Rodriguez Metabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Brussels, Belgium

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Nathalie M Delzenne Metabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Brussels, Belgium

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/80, Il6, Mcp1, Il6, NFkB ) ↓ Lipogenesis ( Fasn ) ↓ Fatty acid oxidation ( Pparγ ) ↓ Adipocytes differentiation (C/EBPα) Neyrinck et al . 2011 HF-fed mice Arabinoxylans AX for 4 weeks 4 weeks HF-AX vs HF (qPCR): ↑ Bifidobacterium spp

Article Type:
Review Article
Collections:
Gut microbiome special collection
DOI:
https://doi.org/10.1530/JOE-20-0499
Volume/Issue:
Volume 249: Issue 1
Free access
Fabio Arturo Iannotti Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Pozzuoli, Campania, Italy

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Vincenzo Di Marzo Director, Joint International Research Unit for the Chemical and Biomolecular Study of the Microbiome in Metabolic Health and Nutrition (JIRU-MicroMeNu) between the Consiglio Nazionale delle Ricerche (CNR, Institute of Biomolecular Chemistry) and Université Laval, Naples, Campania, Italy
Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada

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the liver – increased de novo lipogenesis and insulin resistance, hepatic steatosis and dyslipidemia; (3) in the white adipose tissue – increased energy storage capacity, adipogenesis, lipogenesis, insulin resistance and leptin release, decreased

Article Type:
Review Article
Collections:
Gut microbiome special collection
DOI:
https://doi.org/10.1530/JOE-20-0444
Volume/Issue:
Volume 248: Issue 2
Free access
Marion Régnier UCLouvain, Université Catholique de Louvain, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium

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Matthias Van Hul UCLouvain, Université Catholique de Louvain, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium

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Claude Knauf Université Paul Sabatier, Toulouse III, INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), CHU Purpan, Place du Docteur Baylac, Toulouse Cedex 3, France
European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium

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Patrice D Cani UCLouvain, Université Catholique de Louvain, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium
European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium

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positively associated with fatty acid synthase (FAS), a rate-limiting enzyme of fat-producing lipogenesis ( Wei et al. 2012 ). Defective intestinal lipogenesis in the absence of FAS is detrimental to the palmitoylation of Muc2, a key component of the mucus

Article Type:
Review Article
Collections:
Gut microbiome special collection, Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-20-0473
Volume/Issue:
Volume 248: Issue 2
Free access
Nicole G Barra Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Fernando F Anhê Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Joseph F Cavallari Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Anita M Singh Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Darryl Y Chan Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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Jonathan D Schertzer Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada

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lipogenesis RDA values based on adults aged 19–50 years old. *Vitamin A RDA values are given as retinol activity equivalents (RAE) to account for bioactivity differences of retinol and provitamin A carotenoids, which are then converted into

Article Type:
Review Article
Collections:
Gut microbiome special collection, Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JOE-21-0081
Volume/Issue:
Volume 250: Issue 2
Free access
Erica Yeo Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada

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Patricia L Brubaker Department of Physiology, University of Toronto, Toronto, ON, Canada
Department of Medicine, University of Toronto, Toronto, ON, Canada

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Deborah M Sloboda Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada

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well studied are bacterial SCFAs; SCFAs can be used directly by the host for energy, act as substrates for gluconeogenesis and lipogenesis, and bind receptors present in numerous organ systems ( Tan et al. 2014 ). Activation of SCFA receptors (GPR42

Article Type:
Review Article
Collections:
Gut microbiome special collection
DOI:
https://doi.org/10.1530/JOE-21-0354
Volume/Issue:
Volume 253: Issue 1
Open access