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Institute for Molecular Medicine Finland (FIMM), Helsinki University, Helsinki, Finland
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Institute for Molecular Medicine Finland (FIMM), Helsinki University, Helsinki, Finland
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fasting glucose and C-peptide concentrations with the lowest M-values in SIRD patients both at diagnosis and after 5 years of follow-up ( Zaharia et al. 2019 ). SIRD patients also had the highest frequency of non-alcoholic fatty liver disease (NAFLD
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Stanford Diabetes Research Center, Stanford University, Stanford, California, USA
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). However, it was not until 1996 that back-to-back publications reported the positional cloning of the genes responsible for both MODY1 ( HNF4A ) and MODY3 ( HNF1A ). Prior to this discovery, both transcription factors had recognized roles in the liver but
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Department of Endocrinology and Diabetes, Westmead Hospital, Sydney, New South Wales, Australia
Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales, Australia
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nervous system in the liver or spleen, but a mixture in the kidney capsule which may contribute to the greater transplant success rates observed at this site ( Stokes et al. 2017 ). Alternative strategies of sourcing β-cells Stimulating beta
