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that amongst those with T2DM who had metabolic syndrome compared with those with T2DM but no metabolic syndrome, larger median nerves, increased nerve excitability measures, greater neuropathy clinical scores and lesser related regional corneal nerve
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, aberrant glucose metabolism and dyslipidaemia as features of the metabolic syndrome ( Umapathysivam et al. 2022 ). The proportionate fall in serum testosterone and sex hormone binding globulin (SHBG) concentrations under these circumstances is inherently
Department of Medicine, Monash University, Clayton, Victoria, Australia
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.33, 95% CI 1.01–1.74) and metabolic syndrome (OR 1.53, 1.22–1.91) in subjects with PA compared to those with essential hypertension ( Monticone et al. 2018 ). Consistent with this, treatment of PA has been shown to increase insulin secretion and
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extracellular water and body cell mass ( Hoffman et al. 1995 ). The complexion is pale with thin skin, scarcity of body hairs, and obscure venous vasculature. Investigations may reveal mild normochromic normocytic anaemia, metabolic syndrome, and a fatty liver
Department of Endocrinology and Diabetes, Monash Health, Victoria, Australia
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Department of Endocrinology and Diabetes, Monash Health, Victoria, Australia
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Department of Endocrinology and Diabetes, Monash Health, Victoria, Australia
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manifestations arise in childhood and health impacts evolve across adolescent years and adult life ( Teede et al. 2010 ). PCOS has significant metabolic (obesity, metabolic syndrome, impaired glucose tolerance, type 2 diabetes, cardiovascular risk factors