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Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada
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The gut microbiota and microbiome and the control of metabolism Research started several decades ago, but bloomed only since the beginning of the new century, has provided uncontroversial evidence that the complex ecosystem known as the gut
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richness ( Le Chatelier et al. 2013 ). Individuals with reduced microbial gene richness were also more susceptible to present dys-metabolism and low-grade inflammation in a cohort of French obese or overweight subjects ( Cotillard et al. 2013
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Introduction There is interest in understanding the impact of composition and function of intestinal-resident bacterial communities (i.e. the gut microbiota) on host metabolism. A major challenge is ascribing function to bacterial communities
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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outcomes. We discuss the role of different metabolites produced by the microbiota in host metabolism and how specific nutrients may promote either beneficial or deleterious effects on host health. Role of microbiota in the onset of metabolic diseases
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
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Department of Medicine, University of Toronto, Toronto, ON, Canada
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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
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Introduction To accommodate the dynamic energy demands of pregnancy, while still maintaining metabolic homeostasis, significant alterations to maternal metabolism are required ( Fig. 1 ). Impaired or inappropriate maternal adaptations can