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BIO5 Institute, University of Arizona, Tucson, Arizona, USA
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endocrine system, but also enter the circulation to impact hepatic glucose metabolism ( Shimizu et al. 2019 ), lipid metabolism ( Yu et al. 2019 ), and regulate brown adipose thermogenesis ( Cani et al. 2006 , Christiansen et al. 2018 ). In addition
UofL Superfund Research Center, University of Louisville, Louisville, Kentucky, USA
The Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA
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-specific liver functions including gluconeogenesis and lipid metabolism during different life stages ( Le Magueresse-Battistoni 2021 ). The liver is an indispensable organ in living organisms, based on its critical location in the abdominal cavity along with
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review will summarise recent developments in pregnancy microbiome research and then focus on recent findings highlighting the potential importance of oral bacteria and oral nitrate metabolism in cardiovascular health and in hypertensive pregnancy
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phosphodiesterase 5 (PDE5) metabolism of cGMP ( Motta et al. 2015 ). Sildenafil improved vascular deficiencies without apparent adverse effects on the fetus, such as birth weight differences ( Motta et al. 2015 ). Another PDE5 inhibitor, Tadalafil, reversed
