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The GLP-1R as a model for understanding and exploiting biased agonism in next-generation medicines

Jonathan D Douros

Jonathan D Douros Novo Nordisk Research Center Indianapolis, Indianapolis, Indiana, USA

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Jacek Mokrosinski

Jacek Mokrosinski Novo Nordisk Research Center Indianapolis, Indianapolis, Indiana, USA

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Brian Finan

Brian Finan Novo Nordisk Research Center Indianapolis, Indianapolis, Indiana, USA

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polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis . American Journal of Physiology Endocrinology and Metabolism 284 E931 – E939 . ( https://doi.org/10.1152/ajpendo.00270.2002 ) Pederson RA Satkunarajah M McIntosh