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RISING STARS: Endocrine regulation of metabolic homeostasis via the intestine and gut microbiome

Rachel K Meyer

Rachel K Meyer School of Nutritional Sciences and Wellness, University of Arizona, Tucson, Arizona, USA

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Frank A Duca

Frank A Duca School of Animal and Comparative Biomedical Sciences, College of Agricultural and Life Sciences, University of Arizona, Tucson, Arizona, USA
BIO5 Institute, University of Arizona, Tucson, Arizona, USA

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, and L-cells located in the ileum and colon were thought to exclusively secrete GLP-1. However, GIP and GLP-1 have been shown to colocalize in a subset of human, rat, and porcine small intestinal EECs, indicating simultaneous postprandial secretion of