Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 1 - 10 of 1,487 items for :

  • "programming" x
  • Refine by access: All content x
Clear All
Rui Song Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, California, USA

Search for other papers by Rui Song in
Google Scholar
PubMed Close
,
Xiang-Qun Hu Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, California, USA

Search for other papers by Xiang-Qun Hu in
Google Scholar
PubMed Close
, and
Lubo Zhang Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, California, USA

Search for other papers by Lubo Zhang in
Google Scholar
PubMed Close

). Increasing evidence indicates that glucocorticoids play an essential role in developmental ‘programming’ of health and disease ( Bolt et al. 2001 ). Glucocorticoids are required for the development of lung, brain, gastrointestinal system, renal system and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0672
Volume/Issue:
Volume 242: Issue 1
Free access
Stephen G Matthews Department of Physiology, University of Toronto, Toronto, Ontario, Canada
Departments of Obstetrics & Gynaecology and Medicine, University of Toronto, Toronto, Ontario, Canada
Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada

Search for other papers by Stephen G Matthews in
Google Scholar
PubMed Close
and
Patrick O McGowan Department of Physiology, University of Toronto, Toronto, Ontario, Canada
Department of Biological Sciences and Center for Environmental Epigenetics and Development, University of Toronto, Scarborough, Ontario, Canada
Department of Cell and Systems Biology, Department of Psychology, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Patrick O McGowan in
Google Scholar
PubMed Close

fundamental link between adverse early environments and developmental programming of later disease. The underlying biological mechanisms that connect the perinatal environment with modified long-term health outcomes and represent an intensive area of research

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0057
Volume/Issue:
Volume 242: Issue 1
Free access
G Boaventura
Search for other papers by G Boaventura in
Google Scholar
PubMed Close
,
G Casimiro-Lopes
Search for other papers by G Casimiro-Lopes in
Google Scholar
PubMed Close
,
C C Pazos-Moura Departamento de Ciências Fisiológicas, Instituto de Biofisica Carlos Chagas Filho, 5° Andar, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Avenida 28 de Setembro, 87, Rio de Janeiro 20551-030, Brazil

Search for other papers by C C Pazos-Moura in
Google Scholar
PubMed Close
,
E Oliveira
Search for other papers by E Oliveira in
Google Scholar
PubMed Close
,
P C Lisboa
Search for other papers by P C Lisboa in
Google Scholar
PubMed Close
, and
E G Moura
Search for other papers by E G Moura in
Google Scholar
PubMed Close

. 2011 ). Studies showed that rats participating in training programs of short-duration (10–20 min) and low intensity had higher life expectancies ( Retzlaff et al . 1966 , Edington et al . 1972 ). According to the WHO (2002) , ‘exclusive

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0102
Volume/Issue:
Volume 219: Issue 1
Free access
Patricia C Lisboa Laboratory of Endocrine Physiology, Department of Physiological Sciences, Roberto Alcantara Gomes Biology Institute, State University of Rio de Janeiro, Avenida 28 de setembro, 87, Rio de Janeiro, RJ 20551‐031, Brazil

Search for other papers by Patricia C Lisboa in
Google Scholar
PubMed Close
,
Ellen P S Conceição Laboratory of Endocrine Physiology, Department of Physiological Sciences, Roberto Alcantara Gomes Biology Institute, State University of Rio de Janeiro, Avenida 28 de setembro, 87, Rio de Janeiro, RJ 20551‐031, Brazil

Search for other papers by Ellen P S Conceição in
Google Scholar
PubMed Close
,
Elaine de Oliveira Laboratory of Endocrine Physiology, Department of Physiological Sciences, Roberto Alcantara Gomes Biology Institute, State University of Rio de Janeiro, Avenida 28 de setembro, 87, Rio de Janeiro, RJ 20551‐031, Brazil

Search for other papers by Elaine de Oliveira in
Google Scholar
PubMed Close
, and
Egberto G Moura Laboratory of Endocrine Physiology, Department of Physiological Sciences, Roberto Alcantara Gomes Biology Institute, State University of Rio de Janeiro, Avenida 28 de setembro, 87, Rio de Janeiro, RJ 20551‐031, Brazil

Search for other papers by Egberto G Moura in
Google Scholar
PubMed Close

the nutritional, hormonal and environmental factors observed in the early stages of development have long-term effects on hormonal and metabolic homeostasis. This association can be characterized as a metabolic programming phenomenon, which is defined

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0237
Volume/Issue:
Volume 226: Issue 3
Free access
Luba Sominsky School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia

Search for other papers by Luba Sominsky in
Google Scholar
PubMed Close
,
Christine L Jasoni School of Biomedical Sciences, Centre for Neuroendocrinology, Department of Anatomy, University of Otago, Dunedin, New Zealand

Search for other papers by Christine L Jasoni in
Google Scholar
PubMed Close
,
Hannah R Twigg School of Biomedical Sciences, Centre for Neuroendocrinology, Department of Anatomy, University of Otago, Dunedin, New Zealand

Search for other papers by Hannah R Twigg in
Google Scholar
PubMed Close
, and
Sarah J Spencer School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia

Search for other papers by Sarah J Spencer in
Google Scholar
PubMed Close

poised to be further elaborated and synaptically sculpted by important environmental factors encountered by the freely living individual after birth. Although we will not cover details of development nor prenatal developmental programming in this review

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-17-0722
Volume/Issue:
Volume 237: Issue 2
Free access
Daiana Fornes Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

Search for other papers by Daiana Fornes in
Google Scholar
PubMed Close
,
Florencia Heinecke Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Programming of Metabolic Anomalies, CEFYBO, Buenos Aires, Argentina

Search for other papers by Florencia Heinecke in
Google Scholar
PubMed Close
,
Cintia Romina Gatti Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

Search for other papers by Cintia Romina Gatti in
Google Scholar
PubMed Close
,
Sabrina Lorena Roberti Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

Search for other papers by Sabrina Lorena Roberti in
Google Scholar
PubMed Close
,
Verónica White Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Programming of Metabolic Anomalies, CEFYBO, Buenos Aires, Argentina

Search for other papers by Verónica White in
Google Scholar
PubMed Close
,
Alicia Jawerbaum Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

Search for other papers by Alicia Jawerbaum in
Google Scholar
PubMed Close
, and
Evangelina Capobianco Universidad de Buenos Aires, Facultad de Medicina, Buenos Aires, Argentina
CONICET – Universidad de Buenos Aires, Laboratory of Reproduction and Metabolism, CEFYBO, Buenos Aires, Argentina

Search for other papers by Evangelina Capobianco in
Google Scholar
PubMed Close

Introduction The growing prevalence of obesity and type 2 diabetes has been related not only to sedentary lifestyle, the ingestion of hypercaloric diets and the genetic background but also to the fetal programming of glucose intolerance

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0301
Volume/Issue:
Volume 254: Issue 1
Restricted access
A P Santos-Silva Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by A P Santos-Silva in
Google Scholar
PubMed Close
,
E Oliveira Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by E Oliveira in
Google Scholar
PubMed Close
,
C R Pinheiro Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by C R Pinheiro in
Google Scholar
PubMed Close
,
A C Santana Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by A C Santana in
Google Scholar
PubMed Close
,
C C Nascimento-Saba Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by C C Nascimento-Saba in
Google Scholar
PubMed Close
,
Y Abreu-Villaça Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by Y Abreu-Villaça in
Google Scholar
PubMed Close
,
E G Moura Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by E G Moura in
Google Scholar
PubMed Close
, and
P C Lisboa Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

Search for other papers by P C Lisboa in
Google Scholar
PubMed Close

metabolic programming ( de Moura et al . 2008 , Lisboa et al . 2012 ). Recently, some studies have shown that tobacco exposure in utero is associated with changes in gene methylation profile ( Suter et al . 2010 , 2011 ), and the same event was

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0003
Volume/Issue:
Volume 218: Issue 1
Free access
Jocemara Patrícia Silva de Souza Parrela Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Jocemara Patrícia Silva de Souza Parrela in
Google Scholar
PubMed Close
,
Ingridys Regina Borkenhagen Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Ingridys Regina Borkenhagen in
Google Scholar
PubMed Close
,
Sarah Ramany Faria Salmeron Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Sarah Ramany Faria Salmeron in
Google Scholar
PubMed Close
,
Thalyne Aparecida Leite Lima Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Thalyne Aparecida Leite Lima in
Google Scholar
PubMed Close
,
Ginislene Dias Souza Miranda Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Ginislene Dias Souza Miranda in
Google Scholar
PubMed Close
,
Hercules de Oliveira Costermani Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Hercules de Oliveira Costermani in
Google Scholar
PubMed Close
,
Camila Luiza Rodrigues dos Santos Ricken Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Camila Luiza Rodrigues dos Santos Ricken in
Google Scholar
PubMed Close
,
Ester Vieira Alves Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Ester Vieira Alves in
Google Scholar
PubMed Close
,
Rodrigo Mello Gomes Laboratory of Endocrine Physiology and Metabolism, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil

Search for other papers by Rodrigo Mello Gomes in
Google Scholar
PubMed Close
, and
Júlio Cezar de Oliveira Research Group on Perinatal Programming of Metabolic Diseases: DOHaD Paradigm, Laboratory of Metabolic and Cardiovascular Diseases, Health Education and Research Center (NUPADS), Institute of Health Sciences, Federal University of Mato Grosso, University Campus of Sinop, Sinop, Mato Grosso, Brazil

Search for other papers by Júlio Cezar de Oliveira in
Google Scholar
PubMed Close

et al. 1997 ) famine studies has shown that maternal undernutrition programs long-term metabolic dysfunction in the offspring and that some subtle characteristics of this metabolic impairment depend on the period when the maternal undernutrition

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0427
Volume/Issue:
Volume 255: Issue 1
Free access
Muraly Puttabyatappa Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA

Search for other papers by Muraly Puttabyatappa in
Google Scholar
PubMed Close
,
Robert M Sargis Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

Search for other papers by Robert M Sargis in
Google Scholar
PubMed Close
, and
Vasantha Padmanabhan Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA

Search for other papers by Vasantha Padmanabhan in
Google Scholar
PubMed Close

often remain dormant, requiring an activational step to unmask the programmed phenotypic and behavioral changes. An example of such activational processes is evident in reproductive behavior. While the neurocircuitry required for reproductive behaviors

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-20-0044
Volume/Issue:
Volume 245: Issue 3
Free access
P Nguyen Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by P Nguyen in
Google Scholar
PubMed Close
,
S Khurana Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by S Khurana in
Google Scholar
PubMed Close
,
H Peltsch Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by H Peltsch in
Google Scholar
PubMed Close
,
J Grandbois Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by J Grandbois in
Google Scholar
PubMed Close
,
J Eibl Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by J Eibl in
Google Scholar
PubMed Close
,
J Crispo Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by J Crispo in
Google Scholar
PubMed Close
,
D Ansell Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by D Ansell in
Google Scholar
PubMed Close
, and
T C Tai Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada
Medical Sciences Division, Departments of Biology, Biomolecular Sciences Program, Northern Ontario School of Medicine, Sudbury, Ontario, Canada

Search for other papers by T C Tai in
Google Scholar
PubMed Close

programming. This is mediated in part by adaptation of the fetus to adverse conditions that are encountered during development in utero . Examples of such stressors include maternal nutrient restriction, hypoxia, physical trauma, as well as exposure to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0244
Volume/Issue:
Volume 227: Issue 2
Free access