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Yasminye D Pettway Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

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Diane C Saunders Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA

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Marcela Brissova Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee, USA

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kidney and heart to modulate renal excretion and cardiac function, although these aspects of glucagon physiology are less understood ( Bankir et al. 2016 , Petersen et al. 2018 ). Other secreted factors Beyond glucagon, the human α cell

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