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Department of Physiology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia
Prostate Cancer Research Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia
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Prostate Cancer Research Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia
Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia
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Prostate Cancer Research Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia
Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia
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adult stroma ( Cunha et al. 2002 ). We employed this remarkable instructive property of developmental mesenchyme to direct the differentiation of human embryonic stem cells into mature prostate epithelia ( Taylor et al. 2006 ). We subsequently learnt
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Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia
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. Mesenchymal stem cell GR knockout (Dermo1-Cre) Mesenchymal stem cells are multipotent progenitor cells typically located in the bone marrow that can differentiate into a variety of cell types including chondrocytes, osteoblasts, osteocytes, adipocytes, and
South Australian Adult Genetics Unit, Royal Adelaide Hospital, Adelaide, Australia
Adelaide Medical School, University of Adelaide, Adelaide, Australia
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Garvan Institute of Medical Research, Sydney, NSW, Australia
St Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
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St Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
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Academy for Medical Education, Faculty of Medicine, the University of Queensland, Brisbane, Australia
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Garvan Institute of Medical Research, Sydney, NSW, Australia
St Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
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determined by transcription factor (TF) and hormonal immunohistochemistry. TFs drive maturation from pituitary stem cells: pituitary-specific POU-class homeodomain transcription factor (PIT-1) gives rise to acidophil cells; steroidogenic factor 1 (SF1) gives
Mothers and Babies Research Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia
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derived from embryonic stem cells ( Samuel et al. 2020 ). On the other hand, dutasteride reduced SARS-CoV-2 virus internalisation in human primary alveolar epithelial cells and anti-androgens reduced ACE2 expression and virus infection of lung epithelial
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muscle progenitor cells and muscle protein synthesis and inhibits adipogenic differentiation of pluripotent stem cells ( Herbst & Bhasin 2004 ). Testosterone, following aromatisation to E2, increases growth hormone (GH) secretion from the pituitary
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Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia
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/activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy . Cell Stem Cell 9 433 – 446 . ( https://doi.org/10.1016/j.stem.2011.10.001 ) 22056140 Lotinun S Pearsall RS Davies MV