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Sarah J Richardson Islet Biology Group, Exeter Centre for Excellence in Diabetes (EXCEED), Institute of Biomedical and Clinical Sciences (IBCS), University of Exeter, RILD Level 4, Exeter, UK

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Alberto Pugliese Division of Diabetes Endocrinology and Metabolism, Departments of Medicine, Microbiology and Immunology, Diabetes Research Institute, Leonard Miller School of Medicine, University of Miami, Miami, Florida, USA

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1D pancreas Additional pancreatic pathological abnormalities have been described and appear to contribute to the disease pathogenesis. Inflammation, beta cell stress, and dysfunction Islet inflammation induces stress, protein misfolding

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