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Erica Yeo
Erica Yeo
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
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Patricia L Brubaker
Patricia L Brubaker
Department of Physiology, University of Toronto, Toronto, ON, Canada
Department of Medicine, University of Toronto, Toronto, ON, Canada
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Department of Medicine, University of Toronto, Toronto, ON, Canada
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Deborah M Sloboda
Deborah M Sloboda
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
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well as neurons in the caudal brainstem and hypothalamus ( Müller et al. 2019 ). Transcription factors PAX6, CDX2 and CREB regulate the expression of Gcg in L- and α-cells ( Jin 2008 ). Wnt signaling molecules, GSK-3B and TCF4, are also involved in
Nicole G Barra
Nicole G Barra
Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
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Fernando F Anhê
Fernando F Anhê
Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
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Joseph F Cavallari
Joseph F Cavallari
Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
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Anita M Singh
Anita M Singh
Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
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Darryl Y Chan
Darryl Y Chan
Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
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Jonathan D Schertzer
Jonathan D Schertzer
Department of Biochemistry and Biomedical Sciences, Department of Biochemistry and Biomedical Sciences, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada
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uptake, and by inhibiting the expression of FOXO transcription factors, gluconeogenic enzymes (phosphoenolpyruvate, glucose-6-phosphatase), and negative regulators of PI3K/Akt signaling like phosphatase and tensin homolog protein (PTEN) ( Cameron et al
