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browning ( Wang & Seale 2016 ). The browned white adipocytes begin to express uncoupling protein-1 (UCP1), a specific marker of brown adipose tissue, making white adipose tissue more likely to generate heat and increase the body’s energy consumption. In
The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
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supplementary materials given at the end of this article). Afterwards, the rat BAT fluorescence diminished significantly (probably due to the fusion of rat BAT and mouse BAT), but we were able to detect the rat UCP1 protein and mRNA in the BAT of the