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Renea A Taylor Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia
Department of Physiology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia
Prostate Cancer Research Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia

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Mitchell G Lawrence Department of Physiology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia
Prostate Cancer Research Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia
Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia

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Gail P Risbridger Department of Physiology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia
Prostate Cancer Research Program, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Cabrini Institute, Cabrini Health, Malvern, Victoria, Australia
Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Cancer Program, Monash University, Melbourne, Victoria, Australia

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, PC3 or DU145 cells). The mechanisms of resistance to ARSIs include amplifications, mutations and structural rearrangements of the AR and expression of truncated AR variants ( Shiota et al. 2022 ), and these adaptations can be mirrored in PDXs

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Kirsty G Pringle School of Biomedical Sciences & Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia
Mothers and Babies Research Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia

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Lisa K Philp Australian Prostate Cancer Research Centre - Queensland, Centre for Genomics and Personalised Health & School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Queensland, Australia

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acts on the apelin receptor (APJ) to regulate vascular homeostasis, angiogenesis, myocardial adaptation to stress, and fluid balance, thereby playing a key role in vascular diseases, such as systemic and pulmonary arterial hypertension, myocardial

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Jun Yang Centre of Endocrinology and Metabolism, Hudson Institute of Medical Research, Clayton, Victoria, Australia
Department of Medicine, Monash University, Clayton, Victoria, Australia

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Morag J Young Cardiovascular Endocrinology Laboratory, Discovery & Preclinical Domain, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Timothy J Cole Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia

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Peter J Fuller Centre of Endocrinology and Metabolism, Hudson Institute of Medical Research, Clayton, Victoria, Australia

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control of salt balance and stress-adaptation . Physiology and Behavior 178 13 – 20 . ( https://doi.org/10.1016/j.physbeh.2016.12.045 ) DeRijk RH de Kloet ER Zitman FG & van Leeuwen N 2011 Mineralocorticoid receptor gene variants as

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Eugenie Macfarlane Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia

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Hong Zhou Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia

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Markus J Seibel Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia
Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia

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distress . In Psychopathology of Human Adaptation . Serban G Ed. Boston, MA, USA : Springer . Sher LB Woitge HW Adams DJ Gronowicz GA Krozowski Z Harrison JR & Kream BE 2004 Transgenic expression of 11β-hydroxysteroid dehydrogenase

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