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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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.12165 ) 23425048 Faber CL Deem JD Campos CA Taborsky GJ Morton GJ 2020 CNS control of the endocrine pancreas . Diabetologia 63 2086 – 2094 . ( https://doi.org/10.1007/s00125-020-05204-6 ) 32894319 Fatima Y Doi SA Mamun AA 2015
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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intestinal homeostasis (gut microbiota composition and gut barrier function) directly or indirectly (via microbial-produced metabolites) disturbs the production and secretion of gut endocrine hormones, thereby triggering metabolic diseases ( Fig. 2 ). The
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bacterial components that penetrate host extra-intestinal tissues ( Gérard 2016 , Anhê et al. 2020 a ). The intestine harbors the majority of commensal microbes in humans. Nutrients, bacteria, and host cells that direct immune, endocrine, and metabolic
The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
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Animal Core Facility, Nanjing Medical University, Nanjing, Jiangsu, China
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physiology of the ovary is controlled by the hypothalamus–pituitary–ovarian axis (HPO axis). Many genetic and environmental pathological factors affect ovarian function, causing subfertility or infertility. Thus, alterations in ovarian endocrine activity will
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Division of Advanced Diagnostics, Toronto General Research Institutes, University Health Network, Toronto, Ontario, Canada
Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada
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et al. 2014 ). γ-Aminobutyric acid (GABA) was initially identified as a major neurotransmitter in the CNS, but its actions on pancreatic islet cells and immune cells have been described much more recently. In the peripheral endocrine system, GABA
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molecular diagnosis of GH signaling defects . Endocrine Development 24 118 – 1 27 . ( https://doi.org/10.1159/000342586 ) Fusco A Miele L D'Uonnolo A Forgione A Riccardi L Cefalo C Barini A Bianchi A Giampietro A Cimino V et al
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currently considered as a new approach to weight loss, insulin sensitivity and glucose tolerance, with potential therapeutic effects in the treatment of obesity and cardiovascular diseases. It is well known that white adipose tissue is the main endocrine
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acinar cells was originally reported in the mid-1980s ( Foulis & Stewart 1984 ). By morphometry, T1D pancreata show higher non-exocrine-non-endocrine tissue area to total pancreas area than non-diabetic controls, regardless of age ( Bonnet-Serrano et al
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HU Matthaei S 2007 Metformin . Endocrine Research 32 39 – 57 . ( https://doi.org/10.1080/07435800701743828 ) Sun Y Li J Xiao N Wang M Kou J Qi L Huang F Liu B Liu K 2014 Pharmacological activation of AMPK ameliorates