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Impact of ACE2 on the susceptibility and vulnerability to COVID-19

Kirsty G Pringle

Kirsty G Pringle School of Biomedical Sciences & Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia
Mothers and Babies Research Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia

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Lisa K Philp

Lisa K Philp Australian Prostate Cancer Research Centre - Queensland, Centre for Genomics and Personalised Health & School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Queensland, Australia

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the amount and activity of sACE2 in the circulation are rate-limiting in terms of the production of Ang-(1–7). Locally in intrauterine tissues, the human endometrium (both non-pregnant and pregnant) and placenta express ACE2 ( Marques et al. 2011