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BIO5 Institute, University of Arizona, Tucson, Arizona, USA
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Bain JR , et al. 2016 Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export . Molecular Metabolism 5 538 – 551 . ( https://doi.org/10
UofL Superfund Research Center, University of Louisville, Louisville, Kentucky, USA
The Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA
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. 2015 ). In addition, an experimental study investigating dioxin-like PCB126 effects on hepatic energy metabolism via AHR demonstrated that while female rats were more vulnerable to PCB126-mediated disruption in fatty acid metabolism and lipid
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). Interestingly, the absence of Prevotella in the maternal microbiome has been associated with offspring food allergy ( Vuillermin et al. 2020 ). Prevotella spp. are gram-negative anaerobes, which ferment dietary fibre to produce short-chain fatty acids
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et al. 2022 ). Placental metabolism shifts to greater fatty acid oxidation, greater glycolysis, and reduced ATP production ( Sato et al. 2020 ). A similar PE-like phenotype is caused by sFLT overexpression specifically in the placenta, driven by a