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Rachel K Meyer School of Nutritional Sciences and Wellness, University of Arizona, Tucson, Arizona, USA

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Frank A Duca School of Animal and Comparative Biomedical Sciences, College of Agricultural and Life Sciences, University of Arizona, Tucson, Arizona, USA
BIO5 Institute, University of Arizona, Tucson, Arizona, USA

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function ( Agus et al. 2021 ). For example, short-chain fatty acids (SCFAs) produced by gut bacterial fermentation of ingested fiber induce secretion of glucagon-like peptide 1 (GLP-1) and peptide YY (PYY) from EECs, thereby indirectly impacting the gut

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Banrida Wahlang Department of Medicine, School of Medicine, Division of Gastroenterology, Hepatology & Nutrition, University of Louisville, Louisville, Kentucky, USA
UofL Superfund Research Center, University of Louisville, Louisville, Kentucky, USA
The Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA

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. 2015 ). In addition, an experimental study investigating dioxin-like PCB126 effects on hepatic energy metabolism via AHR demonstrated that while female rats were more vulnerable to PCB126-mediated disruption in fatty acid metabolism and lipid

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Thomas Willmott Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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Elizabeth C Cottrell Maternal and Fetal Health Research Centre, Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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). Interestingly, the absence of Prevotella in the maternal microbiome has been associated with offspring food allergy ( Vuillermin et al. 2020 ). Prevotella spp. are gram-negative anaerobes, which ferment dietary fibre to produce short-chain fatty acids

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Jessica Milano-Foster Division of Animal Sciences, 245 Bond Life Sciences Center, 1201 Rollins Dr University of Missouri, Columbia, Missouri, USA

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Laura C Schulz Department of Obstetrics, Gynecology and Women’s Health, N610 Medical Sciences Building, Columbia, Missouri, USA

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et al. 2022 ). Placental metabolism shifts to greater fatty acid oxidation, greater glycolysis, and reduced ATP production ( Sato et al. 2020 ). A similar PE-like phenotype is caused by sFLT overexpression specifically in the placenta, driven by a

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