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Division of Medical Oncology, University of Washington, Seattle, Washington, USA
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hallmark gene expression patterns and genomic features of small-cell carcinoma, such as TP53 and RB1 loss ( Beltran et al. 2016 ), which are associated with poor outcomes for patients. Cell line experiments observed that restriction of REST activity
UofL Superfund Research Center, University of Louisville, Louisville, Kentucky, USA
The Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA
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appreciated with mechanistic studies attributing the nature of growth hormone secretion, which is pulsatile in males and continuous in females, as a partial reason driving sexually dimorphic hepatic gene expression profiles ( Holloway et al. 2008 , Waxman
Telethon Kids Institute, Perth, Australia
Healthy Environments and Lives (HEAL) Network
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subsequently induce changes in gene expression and protein activity in cells ( Horowitz 2002 , Sonna et al. 2002 ). To reduce the negative impacts of thermal stress on cells, genes associated with increased thermotolerance such as heat shock proteins are
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BIO5 Institute, University of Arizona, Tucson, Arizona, USA
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-1 and improved glucose tolerance ( Zhao et al. 2018 ). The impact of fiber on GLP-1 signaling could be due to increased number of L-cells or expression of the preproglucagon gene ( Massimino et al. 1998 , Everard et al. 2011 , Kaji et al
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gene expression, defects which appear to precede embryonic cardiovascular phenotypes ( Freyer et al. 2017 , Ho et al. 2017 ). The transcription factor Stox1 was first implicated in PE in 2013 through gene association studies in the Netherlands