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Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK
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was used to delete either exon 3 ( Verma et al. 2018 ) or exon 5 ( Semjonous et al. 2011 ) of the Hsd11b1 gene, resulting in a total lack of Hsd11b1 expression. It remains unknown if BM adiposity is altered in these full KO mice. A critical