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The physiology of growth hormone (GH) in adults: translational journey to GH replacement therapy

Ken KY Ho

Ken KY Ho Garvan Institute of Medical Research, St. Vincent’s Hospital and the UNSW Sydney, Sydney, New South Wales, Australia

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Anthony J O’Sullivan

Anthony J O’Sullivan St. George Hospital and the Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia

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Morton G Burt

Morton G Burt Southern Adelaide Diabetes and Endocrine, Flinders Medical Centre and College of Medicine and Public Health, and Flinders University, Adelaide, South Australia, Australia

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led to the search for alternative provocative tests . To date, the following other tests have been validated: GHRH plus arginine test, the glucagon test, and the macimorelin test. Unfortunately, GH-releasing hormone (GHRH) is no longer manufactured