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Abhaya Krishnan Department of Biochemistry, Karpagam University, Coimbatore, Tamil Nadu, India

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Sridhar Muthusami Department of Biochemistry, Karpagam University, Coimbatore, Tamil Nadu, India

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on documenting the available information delineating various hormonal factors and their relevance to alterations in bone mass of women suffering from PCOS. The hormonal factors include GnRH, LH/FSH ratio, estrogens, androgens, insulin, cortisol

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Bethany R L Aykroyd Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

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Simon J Tunster Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

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Amanda N Sferruzzi-Perri Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

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between the mother and fetus and secretes hormones which adapt maternal physiology to support fetal nutrient supply and growth ( Sferruzzi-Perri & Camm 2016 , Napso et al. 2018 ). Previous work has largely focused on understanding the importance of

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Clive W Coen Reproductive Neurobiology, Division of Women's Health, School of Medicine, King's College London, London SE1 1UL, UK

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secretion of gonadotrophic hormone … [and yet] (b) the anterior lobe of the pituitary has at most a very scanty nerve supply’. Despite his focus on reproduction and the unsolved mystery about the route by which hormone-releasing signals access the pituitary

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Alexia Barroso Department of Cell Biology, Physiology, and Immunology, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain
CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain

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Jose Antonio Santos-Marcos CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Lipids and Atherosclerosis Research Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain

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Cecilia Perdices-Lopez Department of Cell Biology, Physiology, and Immunology, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain
CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain

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Ana Vega-Rojas CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Lipids and Atherosclerosis Research Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain

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Miguel Angel Sanchez-Garrido Department of Cell Biology, Physiology, and Immunology, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain
CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain

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Yelizabeta Krylova CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Lipids and Atherosclerosis Research Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain

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Helena Molina-Abril Department of Applied Mathematics I, University of Seville, Seville, Spain

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Claes Ohlsson Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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Pablo Perez-Martinez CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Lipids and Atherosclerosis Research Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain

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Matti Poutanen Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland

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Jose Lopez-Miranda CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Lipids and Atherosclerosis Research Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain

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Manuel Tena-Sempere Department of Cell Biology, Physiology, and Immunology, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), University of Cordoba, Reina Sofia University Hospital, Cordoba, Spain
CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland

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Antonio Camargo CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Cordoba, Spain
Lipids and Atherosclerosis Research Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain

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.g. excessive androgenization in utero) have been linked to the development of insulin resistance and PCOS ( Witchel & Tena-Sempere 2013 ). Hence, gonadal hormones are likely to influence metabolic homeostasis via multiple, frequently redundant, regulatory

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A P Santos-Silva Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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E Oliveira Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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C R Pinheiro Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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A C Santana Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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C C Nascimento-Saba Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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Y Abreu-Villaça Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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E G Moura Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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P C Lisboa Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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weight and food intake were monitored every 4 days. We decapitated two pups per litter at weaning as well as at 180 days, with no prior anesthesia because anesthesia affects hormone and lipid metabolism. Blood samples, adipose tissue, and adrenal gland

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C R Liu Key Laboratory of Hormones and Development, Department of Pathology, Ministry of Health China, Endocrinology Institute of Tianjin Medical University, Tianjin Medical Institute, Tianjin 300070, China

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L Y Li
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F Shi
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X Y Zang
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Y M Liu Key Laboratory of Hormones and Development, Department of Pathology, Ministry of Health China, Endocrinology Institute of Tianjin Medical University, Tianjin Medical Institute, Tianjin 300070, China

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Y Sun
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B H Kan
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Introduction The heart is a major target organ for thyroid hormone (tri-iodothyronine, T 3 ) action. Thyroid hormone exerts its biological effects largely by influencing thyroid hormone-regulated gene expression via interactions with the high

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Jianmei Yang Department of Pediatric Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
Endocrinology, SBMS, Faculty of Medicine, The University of Queensland, St Lucia, Qld, Australia

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Chen Chen Endocrinology, SBMS, Faculty of Medicine, The University of Queensland, St Lucia, Qld, Australia

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Introduction Polycystic ovary syndrome (PCOS) is a common hormonal disturbance affecting 5–15% of reproductive-age women ( Azziz 2016 ). Diagnosis is recommended based on the 2003 Rotterdam criteria and confirmed with two of three criteria

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Andréa Gonçalves Trentin Departatmento Biologia Celular, Embriologia e Genética, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Trindade, Florianópolis, S.C., Brazil

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& Robitaille 2003 , Nedergaard et al. 2003 , Bachoo et al. 2004 ). Astrocytes are mediators of thyroid hormone metabolism in the brain The importance of thyroid hormone for normal brain development is well documented

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Marian Ludgate School of Medicine, Centre for Endocrine and Diabetes Sciences, Cardiff University, Heath Park, Cardiff CF14 4XN, UK

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In a paper entitled ‘Influence of thyroidectomy on thyroxine metabolism and turnover rate in rats’, Nagao et al . (2011) have investigated thyroid hormone kinetics in the hypothyroid state. In a number of carefully performed studies, which rely

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C H J Verhoelst
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V M Darras
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S A Roelens
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G M Artykbaeva
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S Van der Geyten
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Introduction It is well established that thyroid hormones play a crucial role in vertebrate development in general and in brain development and maturation in particular. The impact of thyroid hormones (THS) on the development of the

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