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Sarah J Richardson Islet Biology Group, Exeter Centre for Excellence in Diabetes (EXCEED), Institute of Biomedical and Clinical Sciences (IBCS), University of Exeter, RILD Level 4, Exeter, UK

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Alberto Pugliese Division of Diabetes Endocrinology and Metabolism, Departments of Medicine, Microbiology and Immunology, Diabetes Research Institute, Leonard Miller School of Medicine, University of Miami, Miami, Florida, USA

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in the T1D pancreas, but not in IDIs or in control pancreas ( Colli et al. 2018 , Osum et al. 2018 ). PDL1 expression in beta cells has been linked to interferon alpha and gamma, in the context of alterations induced by islet inflammation, and is

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Robin Kristófi Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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Jan W Eriksson Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden

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group box 1; HSP60, heat shock protein 60; IFN-β, interferon-β; IL-1β, interleukin-1β; IL-6, interleukin-6; iPFK2, inducible phosphofructokinase 2; IRAK1, interleukin-1 receptor-associated kinase 1; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase

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