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Rachel K Meyer School of Nutritional Sciences and Wellness, University of Arizona, Tucson, Arizona, USA

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Frank A Duca School of Animal and Comparative Biomedical Sciences, College of Agricultural and Life Sciences, University of Arizona, Tucson, Arizona, USA
BIO5 Institute, University of Arizona, Tucson, Arizona, USA

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metabolically active tissues ( Fig. 3 ). The majority of SCFAs are removed via first pass by the liver, where they impact hepatic metabolism. For example, butyrate decreases lipogenesis and increases hepatic oxidative respiration and beta-oxidation via

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Banrida Wahlang Department of Medicine, School of Medicine, Division of Gastroenterology, Hepatology & Nutrition, University of Louisville, Louisville, Kentucky, USA
UofL Superfund Research Center, University of Louisville, Louisville, Kentucky, USA
The Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA

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lipid uptake to the liver and increasing susceptibility to steatosis in females ( Wahlang et al. 2019 b ). In contrast to female mice that favor enhance lipogenesis as an evolutionary strategy to prepare for reproductive needs, male mice appear to

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