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macrophages x

Insulin resistance and type 2 diabetes mellitus x

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Do adipocytes serve as a reservoir for severe acute respiratory syndrome coronavirus-2?

Charlotte Steenblock

Charlotte Steenblock Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Nicole Bechmann

Nicole Bechmann Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany

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Felix Beuschlein

Felix Beuschlein Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), Zürich, Switzerland

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Christian Wolfrum

Christian Wolfrum Department of Health Sciences and Technology, Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland

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Stefan R Bornstein

Stefan R Bornstein Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), Zürich, Switzerland
School of Cardiovascular and Metabolic Medicine and Sciences, Faculty of Life Sciences & Medicine, King’s College London, London, UK

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be separated into populations specific for either visceral or subcutaneous adipose tissue ( Vijay et al. 2020 ). An example of such immune cells is the macrophages, which are heterogeneous and can generally be defined in two separate polarisation

Article Type:: Research Article

Collections:: Insulin resistance and type 2 diabetes mellitus

DOI:: https://doi.org/10.1530/JOE-23-0027

Volume/Issue:: Volume 258: Issue 2

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Role of CD20⁺ T cells in cancer, autoimmunity and obesity

Aryane Cruz Oliveira Pinho

Aryane Cruz Oliveira Pinho CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal
CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal
Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, Coimbra, Portugal

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Paula Laranjeira

Paula Laranjeira CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal
CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal
Flow Cytometry Unit, Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
Coimbra Institute for Clinical and Biomedical Research (iCBR), Group of Environmental Genetics of Oncobiology (CIMAGO), Faculty of Medicine (FMUC), University of Coimbra, Coimbra, Portugal
Clinical Academic Center of Coimbra (CACC), Coimbra, Portugal

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Eugenia Carvalho

Eugenia Carvalho CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal
CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal
Institute for Interdisciplinary Research, University of Coimbra (IIIUC), Casa Costa Alemão, Coimbra, Portugal
APDP-Portuguese Diabetes Association, Lisbon, Portugal

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addition, the increase in intracellular calcium levels induced by CD20 has been linked to an increase in the signaling potential of BCR ( Pavlasova et al. 2018 ). CXCR4 is expressed on multiple cell types, including lymphocytes, macrophages, endothelial

Article Type:: Review Article

Collections:: Insulin resistance and type 2 diabetes mellitus

DOI:: https://doi.org/10.1530/JOE-23-0242

Volume/Issue:: Volume 260: Issue 3

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In vivo models of gestational and type 2 diabetes mellitus characterized by endocrine pancreas cell impairments

Sandra K Szlapinski

Sandra K Szlapinski London, Ontario, Canada

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David J Hill

David J Hill Diabetes, Endocrinology and Metabolism, Lawson Health Research Institute, London, Ontario, Canada
Physiology and Pharmacology, Western University, London, Ontario, Canada

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macrophages accumulate in pancreatic islets toward the final stage of pregnancy in order to mediate the reduction of BCM to prepregnancy levels by phagocytosis ( Endo et al. 2023 ). The process has been suggested to occur via the CXCL10–CXCR3 axis, as