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Division of Medical Oncology, University of Washington, Seattle, Washington, USA
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from the surrounding microenvironment recruits macrophages, and neutrophils to the tumor which can contribute to aggressive tumor behavior and increased invasive potential ( Marques et al. 2019 ). Subsets of immune cells thought to closely interact
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attributable to immune activation, including cytokine release, natural killer cell and macrophage activation, and activation of complement ( Clark et al. 1998 ). However, the lack of conclusive evidence for hypertension suggests that immune incompatibility