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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
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Department of Medicine, University of Toronto, Toronto, ON, Canada
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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
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) Bouter K Bakker GJ Levin E Hartstra AV Kootte RS Udayappan SD Katiraei S Bahler L Gilijamse PW Tremaroli V 2018 Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects . Clinical and
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transfer (FMT) interventions in humans ( Vrieze et al. 2012 ). By infusing the intestinal microbiota from lean donors to individuals with metabolic syndrome, an improvement of insulin sensitivity and an increased abundance of butyrate-producing bacteria
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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European Associated Laboratory (EAL) ‘NeuroMicrobiota’, Brussels/Toulouse, Belgium
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beneficial effects of inulin on HFD-induced low-grade inflammation and metabolic syndrome ( Zou et al. 2018 ). They demonstrated that IL-22, which is already known to protect against several intestinal infections ( Zheng et al. 2008 , Zhong et al. 2019
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Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada
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to the latter several features of the metabolic syndrome ( Koren et al. 2012 , Ellekilde et al. 2014 ). Conversely, in a clinical study, transfer of intestinal microbiota from lean donors increased insulin sensitivity in individuals with
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controlled trials have tested supplementing selenium in patients with polycystic ovary syndrome, cardiovascular disease, and diabetes, but the effects of supplementation on metabolic parameters such as glucose tolerance, insulin sensitivity, beta