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the content of the review. We also thank Dylan Sarbaugh and Cell, Stem Cell and Development Program graduate students for their critical reading of the manuscript. References Ackermann AM Wang Z Schug J Naji A & Kaestner KH 2016
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-like cells derived from embryonic stem (ES) cells, though there are notable exceptions ( Li et al. 2020 , Sachs et al. 2020 , Weng et al. 2020 , Tritschler et al. 2022 ). While the function of many of these α cell-specific or ‘identity’ genes has
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pancreatectomy. These issues surrounding the use of the liver as a transplantation site have important implications for fields developing other more experimental approaches to the restoration of islet function that propose using stem cell and xenogenic animal
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Introduction Glucagon is a 29 amino acid pancreatic peptide hormone secreted by the pancreatic alpha cells. It is derived from the precursor hormone proglucagon, which is also a precursor for glucagon-like gut peptides ( Sandoval & D