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Department of Endocrinology and Diabetes, Westmead Hospital, Sydney, New South Wales, Australia
Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales, Australia
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and endothelium that is damaged during enzymatic dissociation of islets. Mesenchymal stem cells (MSC), implicated in tissue repair and maintenance of cellular homeostasis, secrete factors with anti-inflammatory, proangiogenic and regenerative
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Stanford Diabetes Research Center, Stanford University, Stanford, California, USA
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et al. demonstrated β-like cells generated from in vitro differentiated induced pluripotent stem cells (iPSCs) from individuals carrying INS mutations have diminished β-cell proliferation, leading to a decreased β-cell mass, likely playing a role