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The glucocorticoid receptor in skeletal health and disease: insights from targeted knockout mice

Eugenie Macfarlane

Eugenie Macfarlane Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia

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Hong Zhou

Hong Zhou Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia

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Markus J Seibel

Markus J Seibel Bone Research Program, ANZAC Research Institute, The University of Sydney, Australia
Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia

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play a pivotal role in chronobiology by synchronising the body’s biological clocks and hence harmonising circadian rhythms across different organs and tissues. These diverse actions of glucocorticoids are mediated via the glucocorticoid receptor (GR