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Lauren Brady Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Center, Seattle, Washington, USA

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Peter S Nelson Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Center, Seattle, Washington, USA
Division of Medical Oncology, University of Washington, Seattle, Washington, USA

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receptor (AR), a transcription factor activated by androgenic hormones such as testosterone and dihydrotestosterone (DHT). Testosterone, the most common androgen, is metabolized into DHT, which is a more active hormone capable of increased AR binding

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Banrida Wahlang Department of Medicine, School of Medicine, Division of Gastroenterology, Hepatology & Nutrition, University of Louisville, Louisville, Kentucky, USA
UofL Superfund Research Center, University of Louisville, Louisville, Kentucky, USA
The Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, Kentucky, USA

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downregulate transcription factors that co-regulate sexually dimorphic gene expression along with STATB5 including the male-biased activator – hepatocyte nuclear factor 4 alpha (HNF4α) in mouse liver ( Wahlang et al. 2019 b , Cholico et al. 2022 ), while

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Jessica Milano-Foster Division of Animal Sciences, 245 Bond Life Sciences Center, 1201 Rollins Dr University of Missouri, Columbia, Missouri, USA

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Laura C Schulz Department of Obstetrics, Gynecology and Women’s Health, N610 Medical Sciences Building, Columbia, Missouri, USA

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gene expression, defects which appear to precede embryonic cardiovascular phenotypes ( Freyer et al. 2017 , Ho et al. 2017 ). The transcription factor Stox1 was first implicated in PE in 2013 through gene association studies in the Netherlands

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Rachel K Meyer School of Nutritional Sciences and Wellness, University of Arizona, Tucson, Arizona, USA

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Frank A Duca School of Animal and Comparative Biomedical Sciences, College of Agricultural and Life Sciences, University of Arizona, Tucson, Arizona, USA
BIO5 Institute, University of Arizona, Tucson, Arizona, USA

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(PKB) signaling, inactivation of the forkhead transcription factor FoxO1, and down-regulation of bax expression . Journal of Biological Chemistry 280 22297 – 22307 . ( https://doi.org/10.1074/jbc.M500540200 ) Kim YC Seok S Zhang Y Ma J Kong

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